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Addition of an Fc-IgG induces receptor clustering and increases the in vitro efficacy and in vivo anti-tumor properties of the thrombospondin-1 type I repeats (3TSR) in a mouse model of advanced stage ovarian cancer.
Matuszewska, Kathy; Ten Kortenaar, Simone; Pereira, Madison; Santry, Lisa A; Petrik, Duncan; Lo, Kin-Ming; Bridle, Byram W; Wootton, Sarah K; Lawler, Jack; Petrik, Jim.
Afiliación
  • Matuszewska K; Department of Biomedical Sciences, University of Guelph, Guelph, ON, United States of America.
  • Ten Kortenaar S; Department of Biomedical Sciences, University of Guelph, Guelph, ON, United States of America.
  • Pereira M; Department of Biomedical Sciences, University of Guelph, Guelph, ON, United States of America.
  • Santry LA; Department of Pathobiology, University of Guelph, Guelph, ON, United States of America.
  • Petrik D; Department of Biomedical Sciences, University of Guelph, Guelph, ON, United States of America.
  • Lo KM; EMD Serono Research & Development Institute, Billerica, MA, United States of America.
  • Bridle BW; Department of Pathobiology, University of Guelph, Guelph, ON, United States of America.
  • Wootton SK; Department of Pathobiology, University of Guelph, Guelph, ON, United States of America.
  • Lawler J; Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, United States of America.
  • Petrik J; Department of Biomedical Sciences, University of Guelph, Guelph, ON, United States of America. Electronic address: jpetrik@uoguelph.ca.
Gynecol Oncol ; 164(1): 154-169, 2022 01.
Article en En | MEDLINE | ID: mdl-34799137
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Neoplasias Ováricas / Inmunoglobulina G / Trombospondina 1 / Inhibidores de la Angiogénesis / Carcinoma Epitelial de Ovario Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans Idioma: En Revista: Gynecol Oncol Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Neoplasias Ováricas / Inmunoglobulina G / Trombospondina 1 / Inhibidores de la Angiogénesis / Carcinoma Epitelial de Ovario Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans Idioma: En Revista: Gynecol Oncol Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos