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Efficacy and Safety of Vilobelimab (IFX-1), a Novel Monoclonal Anti-C5a Antibody, in Patients With Early Severe Sepsis or Septic Shock-A Randomized, Placebo-Controlled, Double-Blind, Multicenter, Phase IIa Trial (SCIENS Study).
Bauer, Michael; Weyland, Andreas; Marx, Gernot; Bloos, Frank; Weber, Stephan; Weiler, Norbert; Kluge, Stefan; Diers, Anja; Simon, Tim Philipp; Lautenschläger, Ingmar; Gründling, Matthias; Jaschinski, Ulrich; Simon, Philipp; Nierhaus, Axel; Moerer, Onnen; Reill, Lorenz; Jörres, Achim; Guo, Renfeng; Loeffler, Markus; Reinhart, Konrad; Riedemann, Niels.
Afiliación
  • Bauer M; Department of Anesthesiology and Intensive Care Medicine, Jena University Hospital, Jena, Germany.
  • Weyland A; Center for Sepsis Control & Care, Jena University Hospital, Jena, Germany.
  • Marx G; Research Center Neurosensory Science, Carl von Ossietzky Universität Oldenburg, Oldenburg, Germany.
  • Bloos F; Department of Intensive and Intermediate Care Medicine, University Hospital RWTH Aachen, Aachen, Germany.
  • Weber S; Department of Anesthesiology and Intensive Care Medicine, Jena University Hospital, Jena, Germany.
  • Weiler N; Center for Sepsis Control & Care, Jena University Hospital, Jena, Germany.
  • Kluge S; ACOMED statistik, Leipzig, Germany.
  • Diers A; Department of Anesthesiology and Intensive Care Medicine, University Medical Center Kiel, Kiel, Germany.
  • Simon TP; Department of Intensive Care Medicine, University Hospital Hamburg-Eppendorf, Hamburg, Germany.
  • Lautenschläger I; Department of Anesthesiology/Intensive Care Medicine/Emergency Medicine/Pain Therapy, University Hospital Oldenburg, Oldenburg, Germany.
  • Gründling M; Department of Intensive and Intermediate Care Medicine, University Hospital RWTH Aachen, Aachen, Germany.
  • Jaschinski U; Department of Anesthesiology and Intensive Care Medicine, University Medical Center Kiel, Kiel, Germany.
  • Simon P; Department of Anesthesiology and Intensive Care Medicine, University Hospital Greifswald, Greifswald, Germany.
  • Nierhaus A; Department of Anesthesiology and Surgical Intensive Care Medicine, University Hospital Augsburg, Augsburg, Germany.
  • Moerer O; Department of Anesthesiology and Intensive Care Medicine, University of Leipzig Medical Centre, Leipzig, Germany.
  • Reill L; Department of Intensive Care Medicine, University Hospital Hamburg-Eppendorf, Hamburg, Germany.
  • Jörres A; Department of Anesthesiology, University Medical Center, Georg-August-University Göttingen, Göttingen, Germany.
  • Guo R; Department of Internal Medicine/Cardiology, Angiology, Nephrology, and Conservative Intensive Care Medicine, Vivantes Klinikum Neukölln, Berlin, Germany.
  • Loeffler M; Department of Nephrology and Medical Intensive Care, Charité-Universitätsmedizin Berlin, Berlin, Germany.
  • Reinhart K; Department of Medicine I, Nephrology, Transplantation and Medical Intensive Care, University Witten/Herdecke, Medical Center Cologne-Merheim, Cologne, Germany.
  • Riedemann N; InflaRx GmbH, Jena, Germany.
Crit Care Explor ; 3(11): e0577, 2021 Nov.
Article en En | MEDLINE | ID: mdl-34806021
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Texto completo: 1 Banco de datos: MEDLINE Tipo de estudio: Clinical_trials Idioma: En Revista: Crit Care Explor Año: 2021 Tipo del documento: Article País de afiliación: Alemania
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Banco de datos: MEDLINE Tipo de estudio: Clinical_trials Idioma: En Revista: Crit Care Explor Año: 2021 Tipo del documento: Article País de afiliación: Alemania