Targeting Infiltrating Myeloid Cells in Gastric Cancer Using a Pretargeted Imaging Strategy Based on Bio-Orthogonal Diels-Alder Click Chemistry and Comparison with <sup>89</sup>Zr-Labeled Anti-CD11b Positron Emission Tomography Imaging.

Zhang, Yingying; Lin, Qingyu; Wang, Tingting; Shi, Dai; Fu, Zhequan; Si, Zhan; Xu, Zhan; Cheng, Yuan; Shi, Hongcheng; Cheng, Dengfeng

Targeting Infiltrating Myeloid Cells in Gastric Cancer Using a Pretargeted Imaging Strategy Based on Bio-Orthogonal Diels-Alder Click Chemistry and Comparison with ⁸⁹Zr-Labeled Anti-CD11b Positron Emission Tomography Imaging.

Zhang, Yingying; Lin, Qingyu; Wang, Tingting; Shi, Dai; Fu, Zhequan; Si, Zhan; Xu, Zhan; Cheng, Yuan; Shi, Hongcheng; Cheng, Dengfeng.

Afiliación

Zhang Y; Department of Nuclear Medicine, Zhongshan Hospital, Fudan University, No. 180 Fenglin Road, Shanghai 200032, People's Republic of China.
Lin Q; Department of Nuclear Medicine, Zhongshan Hospital, Fudan University, No. 180 Fenglin Road, Shanghai 200032, People's Republic of China.
Wang T; Institute of Nuclear Medicine, Fudan University, Shanghai 200032, People's Republic of China.
Shi D; Shanghai Institute of Medical Imaging, Shanghai 200032, People's Republic of China.
Fu Z; Department of Nuclear Medicine, Zhongshan Hospital, Fudan University, No. 180 Fenglin Road, Shanghai 200032, People's Republic of China.
Si Z; Department of Nuclear Medicine, Zhongshan Hospital, Fudan University, No. 180 Fenglin Road, Shanghai 200032, People's Republic of China.
Xu Z; Department of Nuclear Medicine, Zhongshan Hospital, Fudan University, No. 180 Fenglin Road, Shanghai 200032, People's Republic of China.
Cheng Y; Department of Nuclear Medicine, Zhongshan Hospital, Fudan University, No. 180 Fenglin Road, Shanghai 200032, People's Republic of China.
Shi H; Department of Nuclear Medicine, Zhongshan Hospital, Fudan University, No. 180 Fenglin Road, Shanghai 200032, People's Republic of China.
Cheng D; Department of Nuclear Medicine, Zhongshan Hospital, Fudan University, No. 180 Fenglin Road, Shanghai 200032, People's Republic of China.

Mol Pharm ; 19(1): 246-257, 2022 01 03.

Article en En | MEDLINE | ID: mdl-34816721

Asunto(s)

Antígeno CD11b/metabolismo; Química Clic/métodos; Células Mieloides/metabolismo; Radioisótopos; Neoplasias Gástricas/metabolismo; Circonio; Animales; Línea Celular Tumoral; Femenino; Citometría de Flujo; Humanos; Inmunoterapia/métodos; Ratones; Ratones Endogámicos BALB C; Ratones Desnudos; Células Mieloides/efectos de los fármacos; Trasplante de Neoplasias; Compuestos Organometálicos; Tomografía de Emisión de Positrones/métodos; Neoplasias Gástricas/diagnóstico; Neoplasias Gástricas/diagnóstico por imagen; Neoplasias Gástricas/terapia; Microambiente Tumoral

Palabras clave

Zr-89; anti-CD11b; click chemistry; gastric cancer; pretargeted

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Radioisótopos / Neoplasias Gástricas / Circonio / Células Mieloides / Antígeno CD11b / Química Clic Tipo de estudio: Diagnostic_studies / Prognostic_studies / Screening_studies Límite: Animals / Female / Humans Idioma: En Revista: Mol Pharm Asunto de la revista: BIOLOGIA MOLECULAR / FARMACIA / FARMACOLOGIA Año: 2022 Tipo del documento: Article

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