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Tenofovir disoproxil fumarate directly ameliorates liver fibrosis by inducing hepatic stellate cell apoptosis via downregulation of PI3K/Akt/mTOR signaling pathway.
Lee, Sung Won; Kim, Sung Min; Hur, Wonhee; Kang, Byung-Yoon; Lee, Hae Lim; Nam, Heechul; Yoo, Sun Hong; Sung, Pil Soo; Kwon, Jung Hyun; Jang, Jeong Won; Kim, Seong-Jun; Yoon, Seung Kew.
Afiliación
  • Lee SW; Department of Biomedicine & Health Sciences, The Catholic University Liver Research Centre, POSTECH-Catholic Biomedical Engineering Institute, The Catholic University of Korea, Seoul, Republic of Korea.
  • Kim SM; Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
  • Hur W; Department of Biomedicine & Health Sciences, The Catholic University Liver Research Centre, POSTECH-Catholic Biomedical Engineering Institute, The Catholic University of Korea, Seoul, Republic of Korea.
  • Kang BY; Department of Biomedicine & Health Sciences, The Catholic University Liver Research Centre, POSTECH-Catholic Biomedical Engineering Institute, The Catholic University of Korea, Seoul, Republic of Korea.
  • Lee HL; Department of Biomedicine & Health Sciences, The Catholic University Liver Research Centre, POSTECH-Catholic Biomedical Engineering Institute, The Catholic University of Korea, Seoul, Republic of Korea.
  • Nam H; Department of Biomedicine & Health Sciences, The Catholic University Liver Research Centre, POSTECH-Catholic Biomedical Engineering Institute, The Catholic University of Korea, Seoul, Republic of Korea.
  • Yoo SH; Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
  • Sung PS; Department of Biomedicine & Health Sciences, The Catholic University Liver Research Centre, POSTECH-Catholic Biomedical Engineering Institute, The Catholic University of Korea, Seoul, Republic of Korea.
  • Kwon JH; Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
  • Jang JW; Department of Biomedicine & Health Sciences, The Catholic University Liver Research Centre, POSTECH-Catholic Biomedical Engineering Institute, The Catholic University of Korea, Seoul, Republic of Korea.
  • Kim SJ; Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
  • Yoon SK; Department of Biomedicine & Health Sciences, The Catholic University Liver Research Centre, POSTECH-Catholic Biomedical Engineering Institute, The Catholic University of Korea, Seoul, Republic of Korea.
PLoS One ; 16(12): e0261067, 2021.
Article en En | MEDLINE | ID: mdl-34879114
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Regulación de la Expresión Génica / Apoptosis / Fosfatidilinositol 3-Quinasas / Proteínas Proto-Oncogénicas c-akt / Células Estrelladas Hepáticas / Serina-Treonina Quinasas TOR / Tenofovir / Cirrosis Hepática Límite: Animals / Humans / Male Idioma: En Revista: PLoS One Asunto de la revista: CIENCIA / MEDICINA Año: 2021 Tipo del documento: Article
Texto completo
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Regulación de la Expresión Génica / Apoptosis / Fosfatidilinositol 3-Quinasas / Proteínas Proto-Oncogénicas c-akt / Células Estrelladas Hepáticas / Serina-Treonina Quinasas TOR / Tenofovir / Cirrosis Hepática Límite: Animals / Humans / Male Idioma: En Revista: PLoS One Asunto de la revista: CIENCIA / MEDICINA Año: 2021 Tipo del documento: Article