SUMOylation of Matrix Protein M1 and Filamentous Morphology Collectively Contribute to the Replication and Virulence of Highly Pathogenic H5N1 Avian Influenza Viruses in Mammals.

Guo, Jing; Chen, Jianing; Li, Yuanyuan; Li, Yanbing; Deng, Guohua; Shi, Jianzhong; Liu, Liling; Chen, Hualan; Li, Xuyong

Guo, Jing; Chen, Jianing; Li, Yuanyuan; Li, Yanbing; Deng, Guohua; Shi, Jianzhong; Liu, Liling; Chen, Hualan; Li, Xuyong.

Afiliación

Guo J; College of Agronomy, Liaocheng Universitygrid.411351.3, Liaocheng, China.
Chen J; State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, China.
Li Y; State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, China.
Li Y; State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, China.
Deng G; State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, China.
Shi J; State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, China.
Liu L; State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, China.
Chen H; State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, China.
Li X; State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, China.

J Virol ; 96(4): e0163021, 2022 02 23.

Article en En | MEDLINE | ID: mdl-34908445

Asunto(s)

Subtipo H5N1 del Virus de la Influenza A/fisiología; Subtipo H5N1 del Virus de la Influenza A/patogenicidad; Infecciones por Orthomyxoviridae/virología; Proteínas de la Matriz Viral/metabolismo; Replicación Viral; Transporte Activo de Núcleo Celular; Animales; Núcleo Celular/metabolismo; Perros; Subtipo H5N1 del Virus de la Influenza A/metabolismo; Subtipo H5N1 del Virus de la Influenza A/ultraestructura; Células de Riñón Canino Madin Darby; Ratones; Mutación; Infecciones por Orthomyxoviridae/metabolismo; Estabilidad Proteica; Ribonucleoproteínas/metabolismo; Sumoilación; Proteínas de la Matriz Viral/genética; Virión/ultraestructura; Virulencia/genética; Replicación Viral/genética

Palabras clave

H5N1; M1; SUMOylation; avian influenza virus; morphology; pathogenicity

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Replicación Viral / Proteínas de la Matriz Viral / Infecciones por Orthomyxoviridae / Subtipo H5N1 del Virus de la Influenza A Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: J Virol Año: 2022 Tipo del documento: Article País de afiliación: China

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