Relapsing cerebral atypical teratoid/rhabdoid tumor after trimodality therapy: A case report.
Medicine (Baltimore)
; 100(47): e27986, 2021 11 24.
Article
en En
| MEDLINE
| ID: mdl-34964793
ABSTRACT
INTRODUCTION:
Atypical teratoid rhabdoid tumor (AT/RT) is a high-grade embryonal malignant neoplasm of the central nervous system. It is rare and most often diagnosed in children <4âyears of age. The biological manifestations of AT/RTs are highly malignant and have a very poor prognosis. Here, we present the case of a 16-year-old boy with AT/RT in the right parietal lobe and with a dismal outcome. PATIENT CONCERNS A 16-year-old male boy presented with a headache after waking up for 1 year without obvious cause. The pain was persistent and dull, mainly in the right orbital, and was slightly relieved after pressing the orbital. Occasionally, nausea and vomiting occurred, and the vomiting was gastric contents. Examination and head computed tomography performed at a local hospital revealed a space-occupying lesion in the right parietal lobe. The patient was then transferred to our hospital for further diagnosis and treatment. DIAGNOSIS The patient underwent craniotomy and gross total excision of the tumor. Further histologic examination of the tumor was identified (space-occupying lesion in the right parietal lobe) AT/RT, World Health Organization grade IV.INTERVENTIONS:
The patient was transferred to the oncology department for radiotherapy and chemotherapy after surgery recovery.OUTCOMES:
The patient did not comply with the advice for adjuvant chemotherapy regularly and the tumor recurred rapidly. Finally, the patient died after 18âmonths after the definitive surgery.CONCLUSION:
In conclusion, in the presence of a tumor with peripheral cystic components or hemorrhage in young children, a diagnosis of AT/RT must always be considered. Patients must follow the doctor's advice for active treatment. All relevant data are within the paper and its Supporting Information files.
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Lóbulo Parietal
/
Teratoma
/
Neoplasias Encefálicas
/
Tumor Rabdoide
/
Cefalea
Tipo de estudio:
Prognostic_studies
Límite:
Adolescent
/
Humans
/
Male
Idioma:
En
Revista:
Medicine (Baltimore)
Año:
2021
Tipo del documento:
Article
País de afiliación:
China