Synthesis, carbonic anhydrase enzyme inhibition evaluations, and anticancer studies of sulfonamide based thiadiazole derivatives.

Bahadur, Ali; Iqbal, Shahid; Muneer, Saiqa; Alsaab, Hashem O; Awwad, Nasser S; Ibrahium, Hala A

Bahadur, Ali; Iqbal, Shahid; Muneer, Saiqa; Alsaab, Hashem O; Awwad, Nasser S; Ibrahium, Hala A.

Afiliación

Bahadur A; Department of Transdisciplinary Studies, Graduate School of Convergence Science and Technology, Seoul National University, Seoul 08826, South Korea. Electronic address: alibahadur138@snu.ac.com.
Iqbal S; School of Chemistry and Materials Engineering, Huizhou University, Huizhou 516007, Guangdong, China. Electronic address: shahidiqbal@hzu.edu.cn.
Muneer S; School of Chemistry and Molecular Biosciences, University of Queensland, St Lucia, Brisbane 4072, Australia.
Alsaab HO; Department of Pharmaceutics and Pharmaceutical Technology, Taif University, P.O. Box 11099, Taif 21944, Saudi Arabia.
Awwad NS; Chemistry Department, Faculty of Science, King Khalid University, P.O. Box 9004, Abha 61413, Saudi Arabia.
Ibrahium HA; Biology Department, Faculty of Science, King Khalid University, P.O. Box 9004, Abha 61413, Saudi Arabia; Department of Semi Pilot Plant, Nuclear Materials Authority, P.O. Box 530, El Maadi, Egypt.

Bioorg Med Chem Lett ; 57: 128520, 2022 02 01.

Article en En | MEDLINE | ID: mdl-34965467

Asunto(s)

Antineoplásicos/farmacología; Inhibidores de Anhidrasa Carbónica/farmacología; Sulfonamidas/farmacología; Tiadiazoles/farmacología; Animales; Antineoplásicos/síntesis química; Antineoplásicos/metabolismo; Biocatálisis; Anhidrasa Carbónica II/química; Anhidrasa Carbónica II/metabolismo; Inhibidores de Anhidrasa Carbónica/síntesis química; Inhibidores de Anhidrasa Carbónica/metabolismo; Dominio Catalítico; Bovinos; Ensayos de Selección de Medicamentos Antitumorales; Humanos; Células MCF-7; Simulación del Acoplamiento Molecular; Unión Proteica; Sulfonamidas/síntesis química; Sulfonamidas/metabolismo; Tiadiazoles/síntesis química; Tiadiazoles/metabolismo

Palabras clave

Anticancer studies; Carbonic anhydrase; Inhibition evaluations; Sulfonamides; Thiadiazole

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Sulfonamidas / Tiadiazoles / Inhibidores de Anhidrasa Carbónica / Antineoplásicos Límite: Animals / Humans Idioma: En Revista: Bioorg Med Chem Lett Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2022 Tipo del documento: Article

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