Potency and metabolic stability: a molecular hybrid case in the design of novel PF74-like small molecules targeting HIV-1 capsid protein.

Sahani, Rajkumar Lalji; Akther, Thamina; Cilento, Maria E; Castaner, Andres Emanuelli; Zhang, Huanchun; Kirby, Karen A; Xie, Jiashu; Sarafianos, Stefan G; Wang, Zhengqiang.

Afiliación

Sahani RL; Center for Drug Design, College of Pharmacy, University of Minnesota Minneapolis MN 55455 USA wangx472@umn.edu.
Akther T; Center for Drug Design, College of Pharmacy, University of Minnesota Minneapolis MN 55455 USA wangx472@umn.edu.
Cilento ME; Laboratory of Biochemical Pharmacology, Department of Pediatrics, Emory University School of Medicine Atlanta GA 30322 USA.
Castaner AE; Laboratory of Biochemical Pharmacology, Department of Pediatrics, Emory University School of Medicine Atlanta GA 30322 USA.
Zhang H; Laboratory of Biochemical Pharmacology, Department of Pediatrics, Emory University School of Medicine Atlanta GA 30322 USA.
Kirby KA; Laboratory of Biochemical Pharmacology, Department of Pediatrics, Emory University School of Medicine Atlanta GA 30322 USA.
Xie J; Children's Healthcare of Atlanta Atlanta GA 30322 USA.
Sarafianos SG; Center for Drug Design, College of Pharmacy, University of Minnesota Minneapolis MN 55455 USA wangx472@umn.edu.
Wang Z; Laboratory of Biochemical Pharmacology, Department of Pediatrics, Emory University School of Medicine Atlanta GA 30322 USA.

RSC Med Chem ; 12(12): 2031-2044, 2021 Dec 15.

Article en En | MEDLINE | ID: mdl-35028563

Texto completo: 1 Banco de datos: MEDLINE Idioma: En Revista: RSC Med Chem Año: 2021 Tipo del documento: Article

Texto completo: 1 Banco de datos: MEDLINE Idioma: En Revista: RSC Med Chem Año: 2021 Tipo del documento: Article