Integrated view of molecular diagnosis and prognosis of dengue viral infection: future prospect of exosomes biomarkers.
Mol Cell Biochem
; 477(3): 815-832, 2022 Mar.
Article
en En
| MEDLINE
| ID: mdl-35059925
ABSTRACT
Dengue viruses (DENVs) are the viruses responsible for dengue infection which affects lungs, liver, heart and also other organs of individuals. DENVs consist of the group of four serotypically diverse dengue viruses transmitted in tropical and sub-tropical countries of world. Aedes mosquito is the principal vector which spread the infection from infected person to healthy humans. DENVs can cause different syndromes depending on serotype of virus which range from undifferentiated mild fever to dengue hemorrhagic fever resulting in vascular leakage due to release of cytokine and Dengue shock syndrome with fluid loss and hypotensive shock, or other severe manifestations such as bleeding and organ failure. Increase in dengue cases in pediatric population is a major concern. Transmission of dengue depends on various factors like temperature, rainfall, and distribution of Aedes aegypti mosquitoes. The present review describes a comprehensive overview of dengue, pathophysiology, diagnosis, treatment with an emphasis on potential of exosomes as biomarkers for early prediction of dengue in pediatrics.
Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Dengue
/
Virus del Dengue
/
Exosomas
Tipo de estudio:
Diagnostic_studies
/
Prognostic_studies
Límite:
Animals
/
Humans
Idioma:
En
Revista:
Mol Cell Biochem
Año:
2022
Tipo del documento:
Article
País de afiliación:
India