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Aberrant stromal tissue factor localisation and mycolactone-driven vascular dysfunction, exacerbated by IL-1ß, are linked to fibrin formation in Buruli ulcer lesions.
Hsieh, Louise Tzung-Harn; Dos Santos, Scott J; Hall, Belinda S; Ogbechi, Joy; Loglo, Aloysius D; Salguero, Francisco Javier; Ruf, Marie-Thérèse; Pluschke, Gerd; Simmonds, Rachel E.
Afiliación
  • Hsieh LT; Department of Microbial Sciences, School of Bioscience and Medicine, University of Surrey, Guildford, United Kingdom.
  • Dos Santos SJ; Department of Microbial Sciences, School of Bioscience and Medicine, University of Surrey, Guildford, United Kingdom.
  • Hall BS; Department of Microbial Sciences, School of Bioscience and Medicine, University of Surrey, Guildford, United Kingdom.
  • Ogbechi J; Department of Microbial Sciences, School of Bioscience and Medicine, University of Surrey, Guildford, United Kingdom.
  • Loglo AD; Department of Microbial Sciences, School of Bioscience and Medicine, University of Surrey, Guildford, United Kingdom.
  • Salguero FJ; UK Health Security Agency, Manor Farm Road, Porton Down, Salisbury, United Kingdom.
  • Ruf MT; Swiss Tropical and Public Health Institute, Basel, Switzerland.
  • Pluschke G; University of Basel, Basel, Switzerland.
  • Simmonds RE; Swiss Tropical and Public Health Institute, Basel, Switzerland.
PLoS Pathog ; 18(1): e1010280, 2022 01.
Article en En | MEDLINE | ID: mdl-35100311

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Piel / Tromboplastina / Fibrina / Macrólidos / Mycobacterium ulcerans / Interleucina-1beta / Úlcera de Buruli / Células Endoteliales de la Vena Umbilical Humana Tipo de estudio: Clinical_trials Límite: Adolescent / Adult / Aged / Child / Female / Humans / Male / Middle aged Idioma: En Revista: PLoS Pathog Año: 2022 Tipo del documento: Article País de afiliación: Reino Unido

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Piel / Tromboplastina / Fibrina / Macrólidos / Mycobacterium ulcerans / Interleucina-1beta / Úlcera de Buruli / Células Endoteliales de la Vena Umbilical Humana Tipo de estudio: Clinical_trials Límite: Adolescent / Adult / Aged / Child / Female / Humans / Male / Middle aged Idioma: En Revista: PLoS Pathog Año: 2022 Tipo del documento: Article País de afiliación: Reino Unido