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Augmented lipid-nanoparticle-mediated in vivo genome editing in the lungs and spleen by disrupting Cas9 activity in the liver.
Sago, Cory D; Lokugamage, Melissa P; Loughrey, David; Lindsay, Kevin E; Hincapie, Robert; Krupczak, Brandon R; Kalathoor, Sujay; Sato, Manaka; Echeverri, Elisa Schrader; Fitzgerald, Jordan P; Gan, Zubao; Gamboa, Lena; Paunovska, Kalina; Sanhueza, Carlos A; Hatit, Marine Z C; Finn, M G; Santangelo, Philip J; Dahlman, James E.
Afiliación
  • Sago CD; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA, USA.
  • Lokugamage MP; Beam Therapeutics, Atlanta, GA, USA.
  • Loughrey D; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA, USA.
  • Lindsay KE; Alloy Therapeutics, Lexington, MA, USA.
  • Hincapie R; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA, USA.
  • Krupczak BR; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA, USA.
  • Kalathoor S; School of Chemistry and Biochemistry, Georgia Institute of Technology, Atlanta, GA, USA.
  • Sato M; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA, USA.
  • Echeverri ES; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA, USA.
  • Fitzgerald JP; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA, USA.
  • Gan Z; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA, USA.
  • Gamboa L; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA, USA.
  • Paunovska K; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA, USA.
  • Sanhueza CA; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA, USA.
  • Hatit MZC; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA, USA.
  • Finn MG; School of Chemistry and Biochemistry, Georgia Institute of Technology, Atlanta, GA, USA.
  • Santangelo PJ; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA, USA.
  • Dahlman JE; School of Chemistry and Biochemistry, Georgia Institute of Technology, Atlanta, GA, USA.
Nat Biomed Eng ; 6(2): 157-167, 2022 02.
Article en En | MEDLINE | ID: mdl-35190679

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Nanopartículas / Edición Génica Límite: Animals Idioma: En Revista: Nat Biomed Eng Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Nanopartículas / Edición Génica Límite: Animals Idioma: En Revista: Nat Biomed Eng Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos