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Effector membrane translocation biosensors reveal G protein and ßarrestin coupling profiles of 100 therapeutically relevant GPCRs.
Avet, Charlotte; Mancini, Arturo; Breton, Billy; Le Gouill, Christian; Hauser, Alexander S; Normand, Claire; Kobayashi, Hiroyuki; Gross, Florence; Hogue, Mireille; Lukasheva, Viktoriya; St-Onge, Stéphane; Carrier, Marilyn; Héroux, Madeleine; Morissette, Sandra; Fauman, Eric B; Fortin, Jean-Philippe; Schann, Stephan; Leroy, Xavier; Gloriam, David E; Bouvier, Michel.
Afiliación
  • Avet C; Institute for Research in Immunology and Cancer (IRIC), and Department of Biochemistry and Molecular Medicine, Université de Montréal, Montréal, Canada.
  • Mancini A; Domain Therapeutics North America, Montréal, Canada.
  • Breton B; Domain Therapeutics North America, Montréal, Canada.
  • Le Gouill C; Institute for Research in Immunology and Cancer (IRIC), and Department of Biochemistry and Molecular Medicine, Université de Montréal, Montréal, Canada.
  • Hauser AS; Department of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, Denmark.
  • Normand C; Domain Therapeutics North America, Montréal, Canada.
  • Kobayashi H; Institute for Research in Immunology and Cancer (IRIC), and Department of Biochemistry and Molecular Medicine, Université de Montréal, Montréal, Canada.
  • Gross F; Domain Therapeutics North America, Montréal, Canada.
  • Hogue M; Institute for Research in Immunology and Cancer (IRIC), and Department of Biochemistry and Molecular Medicine, Université de Montréal, Montréal, Canada.
  • Lukasheva V; Institute for Research in Immunology and Cancer (IRIC), and Department of Biochemistry and Molecular Medicine, Université de Montréal, Montréal, Canada.
  • St-Onge S; Institute for Research in Immunology and Cancer (IRIC), and Department of Biochemistry and Molecular Medicine, Université de Montréal, Montréal, Canada.
  • Carrier M; Institute for Research in Immunology and Cancer (IRIC), and Department of Biochemistry and Molecular Medicine, Université de Montréal, Montréal, Canada.
  • Héroux M; Institute for Research in Immunology and Cancer (IRIC), and Department of Biochemistry and Molecular Medicine, Université de Montréal, Montréal, Canada.
  • Morissette S; Domain Therapeutics North America, Montréal, Canada.
  • Fauman EB; Internal Medicine Research Unit, Pfizer Worldwide Research, Development and Medical, Cambridge, United States.
  • Fortin JP; Pfizer Global R&D, Cambridge, United States.
  • Schann S; Domain Therapeutics, Illkirch-Strasbourg, France.
  • Leroy X; Domain Therapeutics, Illkirch-Strasbourg, France.
  • Gloriam DE; Department of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, Denmark.
  • Bouvier M; Institute for Research in Immunology and Cancer (IRIC), and Department of Biochemistry and Molecular Medicine, Université de Montréal, Montréal, Canada.
Elife ; 112022 03 18.
Article en En | MEDLINE | ID: mdl-35302493
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Técnicas Biosensibles / Proteínas de Unión al GTP Límite: Humans Idioma: En Revista: Elife Año: 2022 Tipo del documento: Article País de afiliación: Canadá
Texto completo
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Buscar en Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Técnicas Biosensibles / Proteínas de Unión al GTP Límite: Humans Idioma: En Revista: Elife Año: 2022 Tipo del documento: Article País de afiliación: Canadá