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Reconstructed glycosylase base editors GBE2.0 with enhanced C-to-G base editing efficiency and purity.
Sun, Naxin; Zhao, Dongdong; Li, Siwei; Zhang, Ziteng; Bi, Changhao; Zhang, Xueli.
Afiliación
  • Sun N; Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin 300000, China; Key Laboratory of Systems Microbial Biotechnology, Chinese Academy of Sciences, Tianjin 300000, China.
  • Zhao D; Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin 300000, China; Key Laboratory of Systems Microbial Biotechnology, Chinese Academy of Sciences, Tianjin 300000, China.
  • Li S; Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin 300000, China; Key Laboratory of Systems Microbial Biotechnology, Chinese Academy of Sciences, Tianjin 300000, China.
  • Zhang Z; Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin 300000, China; College of Life Science, Naikai University, Tianjin 300000, China.
  • Bi C; Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin 300000, China; Key Laboratory of Systems Microbial Biotechnology, Chinese Academy of Sciences, Tianjin 300000, China. Electronic address: bi_ch@tib.cas.cn.
  • Zhang X; Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin 300000, China; Key Laboratory of Systems Microbial Biotechnology, Chinese Academy of Sciences, Tianjin 300000, China. Electronic address: zhang_xl@tib.cas.cn.
Mol Ther ; 30(7): 2452-2463, 2022 07 06.
Article en En | MEDLINE | ID: mdl-35381364
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Sistemas CRISPR-Cas / Edición Génica Límite: Animals / Humans Idioma: En Revista: Mol Ther Asunto de la revista: BIOLOGIA MOLECULAR / TERAPEUTICA Año: 2022 Tipo del documento: Article País de afiliación: China
Texto completo
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Sistemas CRISPR-Cas / Edición Génica Límite: Animals / Humans Idioma: En Revista: Mol Ther Asunto de la revista: BIOLOGIA MOLECULAR / TERAPEUTICA Año: 2022 Tipo del documento: Article País de afiliación: China