Transition-metal-catalyzed remote C-H functionalization of thioethers.

In the last decade, transition-metal-catalyzed direct C-H bond functionalization has been recognized as one of most efficient approaches for the derivatization of thioethers. Within this category, both mono- and bidentate-directing group strategies achieved the remote C(sp2)-H and C(sp3)-H functionalization of thioethers, respectively. This review systematically introduces the major advances and their mechanisms in the field of transition-metal-catalyzed remote C-H functionalization of thioethers from 2010 to 2021.