Immune-Nutritional Status as a Novel Prognostic Predictor of Bell's Palsy.
Audiol Neurootol
; 27(5): 418-426, 2022.
Article
en En
| MEDLINE
| ID: mdl-35512660
ABSTRACT
INTRODUCTION:
The prognosis of Bell's palsy, idiopathic facial nerve palsy (FNP), is usually predicted by electroneuronography in subacute phase. However, it would be ideal to establish a reliable and objective examination applicable in acute phase to predict the prognosis of FNP. Immune-nutritional status (INS) calculated from peripheral blood examination is recently reported as the prognostic factor in various disease. However, the validity of INS as the prognostic factor in Bell's palsy is not well known. Thus, we conducted a retrospective study to investigate the usefulness of INS as prognostic predictors of Bell's palsy.METHODS:
We reviewed the medical records of 79 patients with Bell's palsy and divided into two groups as "complete recovery" and "incomplete recovery" groups. Clinical features such as severity of FNP and INS, including neutrophil-lymphocyte ratio (NLR), lymphocyte-monocyte ratio (LMR), prognostic nutritional index (PNI), and controlling nutrition status (CONUT) score, were assessed.RESULTS:
In univariate analysis, statistically significant differences were observed in clinical score of facial movement, NLR, LMR, PNI, and CONUT score at the initial examination between the two groups (p < 0.05). Furthermore, in multivariate analysis, statistically significant differences were also observed in facial movement score and PNI at the initial examination (p < 0.05).CONCLUSION:
Immune and nutritional condition play important roles in the pathogenesis of Bell's palsy, suggesting that INS would be one of the useful prognostic factors in Bell's palsy.Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Parálisis de Bell
/
Parálisis Facial
Tipo de estudio:
Diagnostic_studies
/
Etiology_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Límite:
Humans
Idioma:
En
Revista:
Audiol Neurootol
Asunto de la revista:
AUDIOLOGIA
/
PSICOFISIOLOGIA
Año:
2022
Tipo del documento:
Article
País de afiliación:
Japón