Zileuton, a 5-Lipoxygenase Inhibitor, Attenuates Haemolysate-Induced BV-2 Cell Activation by Suppressing the MyD88/NF-&#954;B Pathway.

Su, Hui-Yuan; Tsai, Yi-Cheng; Tsai, Hung-Pei; Lin, Chih-Lung

Zileuton, a 5-Lipoxygenase Inhibitor, Attenuates Haemolysate-Induced BV-2 Cell Activation by Suppressing the MyD88/NF-κB Pathway.

Su, Hui-Yuan; Tsai, Yi-Cheng; Tsai, Hung-Pei; Lin, Chih-Lung.

Afiliación

Su HY; Department of Surgery, Division of Neurosurgery, Kaohsiung Medical University Hospital, Kaohsiung 807, Taiwan.
Tsai YC; Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 807, Taiwan.
Tsai HP; Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 807, Taiwan.
Lin CL; Department of Surgery, Division of Neurosurgery, Kaohsiung Medical University Hospital, Kaohsiung 807, Taiwan.

Int J Mol Sci ; 23(9)2022 Apr 28.

Article en En | MEDLINE | ID: mdl-35563304

Asunto(s)

FN-kappa B; Hemorragia Subaracnoidea; Animales; Hidroxiurea/análogos & derivados; Lipopolisacáridos/metabolismo; Inhibidores de la Lipooxigenasa/metabolismo; Inhibidores de la Lipooxigenasa/farmacología; Microglía/metabolismo; Factor 88 de Diferenciación Mieloide/metabolismo; FN-kappa B/metabolismo; Transducción de Señal; Hemorragia Subaracnoidea/metabolismo

Palabras clave

5-lipoxygenase; BV-2 cells; microglia; subarachnoid haemorrhage; zileuton

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Hemorragia Subaracnoidea / FN-kappa B Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Int J Mol Sci Año: 2022 Tipo del documento: Article País de afiliación: Taiwán

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