The parcellation of cingulate cortex in neonatal period based on resting-state functional MRI.
Cereb Cortex
; 33(6): 2548-2558, 2023 03 10.
Article
en En
| MEDLINE
| ID: mdl-35689654
ABSTRACT
The human cingulate cortex (CC) is a complex region that is characterized by heterogeneous cytoarchitecture, connectivity, and function, and it is associated with various cognitive functions. The adult CC has been divided into various subregions, and this subdivision is highly consistent with its functional differentiation. However, only a few studies have focused on the function of neonatal CC. The aim of this study was to describe the cingulate segregation and the functional connectivity of each subdivision in full-term neonates (n = 60) based on resting-state functional magnetic resonance imaging. The neonatal CC was divided into three subregions, and each subregion showed specific connectivity patterns. The anterior cingulate cortex was mainly correlated with brain regions related to the salience (affected) network and default mode network (DMN), the midcingulate cortex was related to motor areas, and the posterior cingulate cortex was coupled with DMN. Moreover, we found that the cingulate subregions showed distinct functional profiles with major brain networks, which were defined using independent component analysis, and exhibited functional lateralization. This study provided new insights into the understanding of the functional specialization of neonatal CC, and these findings may have significant clinical implications, especially in predicting neurological disorder.
Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Mapeo Encefálico
/
Giro del Cíngulo
Tipo de estudio:
Prognostic_studies
Límite:
Adult
/
Humans
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Newborn
Idioma:
En
Revista:
Cereb Cortex
Asunto de la revista:
CEREBRO
Año:
2023
Tipo del documento:
Article
País de afiliación:
China