Posttranslational modifications optimize the ability of SARS-CoV-2 spike for effective interaction with host cell receptors.

Kapoor, Karan; Chen, Tianle; Tajkhorshid, Emad

Kapoor, Karan; Chen, Tianle; Tajkhorshid, Emad.

Afiliación

Kapoor K; Theoretical and Computational Biophysics Group, NIH Center for Macromolecular Modeling and Bioinformatics, Beckman Institute for Advanced Science and Technology, Department of Biochemistry, University of Illinois at Urbana-Champaign, Urbana, IL 61801.
Chen T; Center for Biophysics and Quantitative Biology, University of Illinois at Urbana Champaign, Urbana, IL 61801.
Tajkhorshid E; Theoretical and Computational Biophysics Group, NIH Center for Macromolecular Modeling and Bioinformatics, Beckman Institute for Advanced Science and Technology, Department of Biochemistry, University of Illinois at Urbana-Champaign, Urbana, IL 61801.

Proc Natl Acad Sci U S A ; 119(28): e2119761119, 2022 07 12.

Article en En | MEDLINE | ID: mdl-35737823

Asunto(s)

COVID-19; Interacciones Microbiota-Huesped; Procesamiento Proteico-Postraduccional; Receptores de Superficie Celular; SARS-CoV-2; Glicoproteína de la Espiga del Coronavirus; COVID-19/virología; Glicosilación; Humanos; Polisacáridos; Unión Proteica; Receptores de Superficie Celular/metabolismo; Glicoproteína de la Espiga del Coronavirus/genética; Glicoproteína de la Espiga del Coronavirus/metabolismo

Palabras clave

coronaviruses; glycosylation; molecular dynamics; spike protein; structural dynamics

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Procesamiento Proteico-Postraduccional / Receptores de Superficie Celular / Glicoproteína de la Espiga del Coronavirus / Interacciones Microbiota-Huesped / SARS-CoV-2 / COVID-19 Límite: Humans Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2022 Tipo del documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google