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Long-term treatment with the mPXR agonist PCN promotes hepatomegaly and lipid accumulation without hepatocyte proliferation in mice.
Zhang, Yi-Fei; Gao, Yue; Yang, Jie; Jiang, Yi-Ming; Huang, Min; Fan, Shi-Cheng; Bi, Hui-Chang.
Afiliación
  • Zhang YF; Guangdong Provincial Key Laboratory of New Drug Design and Evaluation, School of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou, 510006, China.
  • Gao Y; Guangdong Provincial Key Laboratory of New Drug Design and Evaluation, School of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou, 510006, China.
  • Yang J; Guangdong Provincial Key Laboratory of New Drug Design and Evaluation, School of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou, 510006, China.
  • Jiang YM; Guangdong Provincial Key Laboratory of New Drug Design and Evaluation, School of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou, 510006, China.
  • Huang M; Guangdong Provincial Key Laboratory of New Drug Design and Evaluation, School of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou, 510006, China. huangmin@mail.sysu.edu.cn.
  • Fan SC; Guangdong Provincial Key Laboratory of New Drug Design and Evaluation, School of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou, 510006, China. fanshch3@mail2.sysu.edu.cn.
  • Bi HC; NMPA Key Laboratory for Research and Evaluation of Drug Metabolism, Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, 510515, China. fanshch3@mail2.sysu.edu.cn.
Acta Pharmacol Sin ; 44(1): 169-177, 2023 Jan.
Article en En | MEDLINE | ID: mdl-35773338
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Receptores de Esteroides Límite: Animals Idioma: En Revista: Acta Pharmacol Sin Asunto de la revista: FARMACOLOGIA Año: 2023 Tipo del documento: Article País de afiliación: China
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Receptores de Esteroides Límite: Animals Idioma: En Revista: Acta Pharmacol Sin Asunto de la revista: FARMACOLOGIA Año: 2023 Tipo del documento: Article País de afiliación: China