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A unique peptide-based pharmacophore identifies an inhibitory compound against the A-subunit of Shiga toxin.
Watanabe-Takahashi, Miho; Senda, Miki; Yoshino, Ryunosuke; Hibino, Masahiro; Hama, Shinichiro; Terada, Tohru; Shimizu, Kentaro; Senda, Toshiya; Nishikawa, Kiyotaka.
Afiliación
  • Watanabe-Takahashi M; Department of Molecular Life Sciences, Graduate School of Life and Medical Sciences, Doshisha University, Kyoto, Japan.
  • Senda M; Structural Biology Research Center, Institute of Materials Structure Science, High Energy Accelerator Research Organization (KEK), Ibaraki, Japan.
  • Yoshino R; Department of Biotechnology, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo, Japan.
  • Hibino M; Transborder Medical Research Center, University of Tsukuba, Ibaraki, Japan.
  • Hama S; Department of Molecular Life Sciences, Graduate School of Life and Medical Sciences, Doshisha University, Kyoto, Japan.
  • Terada T; Department of Molecular Life Sciences, Graduate School of Life and Medical Sciences, Doshisha University, Kyoto, Japan.
  • Shimizu K; Department of Biotechnology, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo, Japan.
  • Senda T; Department of Biotechnology, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo, Japan. shimizu@bi.a.u-tokyo.ac.jp.
  • Nishikawa K; Structural Biology Research Center, Institute of Materials Structure Science, High Energy Accelerator Research Organization (KEK), Ibaraki, Japan. toshiya.senda@kek.jp.
Sci Rep ; 12(1): 11443, 2022 07 06.
Article en En | MEDLINE | ID: mdl-35794188
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Infecciones por Escherichia coli / Escherichia coli Enterohemorrágica Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Sci Rep Año: 2022 Tipo del documento: Article País de afiliación: Japón
Texto completo
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XML
PubMed Links
Buscar en Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Infecciones por Escherichia coli / Escherichia coli Enterohemorrágica Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Sci Rep Año: 2022 Tipo del documento: Article País de afiliación: Japón