Repurposing the Antiplatelet Agent Ticlopidine to Counteract the Acute Phase of ER Stress Condition: An Opportunity for Fighting Coronavirus Infections and Cancer.

Tesei, Anna; Cortesi, Michela; Bedeschi, Martina; Marino, Noemi; Rossino, Giacomo; Listro, Roberta; Rossi, Daniela; Linciano, Pasquale; Collina, Simona

Tesei, Anna; Cortesi, Michela; Bedeschi, Martina; Marino, Noemi; Rossino, Giacomo; Listro, Roberta; Rossi, Daniela; Linciano, Pasquale; Collina, Simona.

Afiliación

Tesei A; Biosciences Laboratory, IRCCS Istituto Romagnolo per lo Studio dei Tumori (IRST) "Dino Amadori", 47014 Meldola, Italy.
Cortesi M; Biosciences Laboratory, IRCCS Istituto Romagnolo per lo Studio dei Tumori (IRST) "Dino Amadori", 47014 Meldola, Italy.
Bedeschi M; Biosciences Laboratory, IRCCS Istituto Romagnolo per lo Studio dei Tumori (IRST) "Dino Amadori", 47014 Meldola, Italy.
Marino N; Biosciences Laboratory, IRCCS Istituto Romagnolo per lo Studio dei Tumori (IRST) "Dino Amadori", 47014 Meldola, Italy.
Rossino G; Medicinal Chemistry and Pharmaceutical Technology Section, Department of Drug Sciences, University of Pavia, 27100 Pavia, Italy.
Listro R; Medicinal Chemistry and Pharmaceutical Technology Section, Department of Drug Sciences, University of Pavia, 27100 Pavia, Italy.
Rossi D; Medicinal Chemistry and Pharmaceutical Technology Section, Department of Drug Sciences, University of Pavia, 27100 Pavia, Italy.
Linciano P; Medicinal Chemistry and Pharmaceutical Technology Section, Department of Drug Sciences, University of Pavia, 27100 Pavia, Italy.
Collina S; Medicinal Chemistry and Pharmaceutical Technology Section, Department of Drug Sciences, University of Pavia, 27100 Pavia, Italy.

Molecules ; 27(14)2022 Jul 06.

Article en En | MEDLINE | ID: mdl-35889200

Asunto(s)

Tratamiento Farmacológico de COVID-19; Neoplasias; Reposicionamiento de Medicamentos; Estrés del Retículo Endoplásmico; Humanos; Neoplasias/patología; Inhibidores de Agregación Plaquetaria/farmacología; Inhibidores de Agregación Plaquetaria/uso terapéutico; SARS-CoV-2; Ticlopidina/farmacología; Respuesta de Proteína Desplegada

Palabras clave

COVID-19; ER stress; P2Y12 inhibitors; cancer; endoplasmic reticulum (ER); sigma 1 receptor (S1R); terminal UPR; ticlopidine

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Tratamiento Farmacológico de COVID-19 / Neoplasias Límite: Humans Idioma: En Revista: Molecules Asunto de la revista: BIOLOGIA Año: 2022 Tipo del documento: Article País de afiliación: Italia

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