Phenotypic and genetic classification of diabetes.
Diabetologia
; 65(11): 1758-1769, 2022 11.
Article
en En
| MEDLINE
| ID: mdl-35953726
ABSTRACT
The historical subclassification of diabetes into predominantly types 1 and 2 is well appreciated to inadequately capture the heterogeneity seen in patient presentations, disease course, response to therapy and disease complications. This review summarises proposed data-driven approaches to further refine diabetes subtypes using clinical phenotypes and/or genetic information. We highlight the benefits as well as the limitations of these subclassification schemas, including practical barriers to their implementation that would need to be overcome before incorporation into clinical practice.
Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Diabetes Mellitus Tipo 2
Tipo de estudio:
Prognostic_studies
Límite:
Humans
Idioma:
En
Revista:
Diabetologia
Año:
2022
Tipo del documento:
Article
País de afiliación:
Estados Unidos