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Discovery of acyl ureas as highly selective small molecule CSF1R kinase inhibitors.
Caldwell, Timothy M; Kaufman, Michael D; Wise, Scott C; Mi Ahn, Yu; Hood, Molly M; Lu, Wei-Ping; Patt, William C; Samarakoon, Thiwanka; Vogeti, Lakshminarayana; Vogeti, Subha; Yates, Karen M; Bulfer, Stacie L; Le Bourdonnec, Bertrand; Smith, Bryan D; Flynn, Daniel L.
Afiliación
  • Caldwell TM; Deciphera Pharmaceuticals, LLC, Waltham, MA 02451, United States.
  • Kaufman MD; Deciphera Pharmaceuticals, LLC, Waltham, MA 02451, United States.
  • Wise SC; Deciphera Pharmaceuticals, LLC, Waltham, MA 02451, United States.
  • Mi Ahn Y; Deciphera Pharmaceuticals, LLC, Waltham, MA 02451, United States.
  • Hood MM; Deciphera Pharmaceuticals, LLC, Waltham, MA 02451, United States.
  • Lu WP; Deciphera Pharmaceuticals, LLC, Waltham, MA 02451, United States.
  • Patt WC; Deciphera Pharmaceuticals, LLC, Waltham, MA 02451, United States.
  • Samarakoon T; Deciphera Pharmaceuticals, LLC, Waltham, MA 02451, United States.
  • Vogeti L; Deciphera Pharmaceuticals, LLC, Waltham, MA 02451, United States.
  • Vogeti S; Deciphera Pharmaceuticals, LLC, Waltham, MA 02451, United States.
  • Yates KM; Deciphera Pharmaceuticals, LLC, Waltham, MA 02451, United States.
  • Bulfer SL; Deciphera Pharmaceuticals, LLC, Waltham, MA 02451, United States.
  • Le Bourdonnec B; Deciphera Pharmaceuticals, LLC, Waltham, MA 02451, United States.
  • Smith BD; Deciphera Pharmaceuticals, LLC, Waltham, MA 02451, United States.
  • Flynn DL; Deciphera Pharmaceuticals, LLC, Waltham, MA 02451, United States. Electronic address: dflynn@deciphera.com.
Bioorg Med Chem Lett ; 74: 128929, 2022 10 15.
Article en En | MEDLINE | ID: mdl-35961461
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Urea / Proteínas Tirosina Quinasas Receptoras Tipo de estudio: Prognostic_studies Idioma: En Revista: Bioorg Med Chem Lett Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Urea / Proteínas Tirosina Quinasas Receptoras Tipo de estudio: Prognostic_studies Idioma: En Revista: Bioorg Med Chem Lett Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos