Deficiency of Ninjurin1 attenuates LPS/D-galactosamine-induced acute liver failure by reducing TNF-&#945;-induced apoptosis in hepatocytes.

Kim, Min Woo; Kang, Ju-Hee; Jung, Hyun Jin; Park, Se Yong; Hwang, Jong-Ik; Seong, Je Kyung; Yoon, Yeo Sung; Oh, Seung Hyun

Deficiency of Ninjurin1 attenuates LPS/D-galactosamine-induced acute liver failure by reducing TNF-α-induced apoptosis in hepatocytes.

Kim, Min Woo; Kang, Ju-Hee; Jung, Hyun Jin; Park, Se Yong; Hwang, Jong-Ik; Seong, Je Kyung; Yoon, Yeo Sung; Oh, Seung Hyun.

Afiliación

Kim MW; Department of Anatomy and Cell Biology, College of Veterinary Medicine, Seoul National University, Seoul, South Korea.
Kang JH; College of Pharmacy, Gachon University, Incheon, South Korea.
Jung HJ; College of Pharmacy, Gachon University, Incheon, South Korea.
Park SY; Department of Anatomy and Cell Biology, College of Veterinary Medicine, Seoul National University, Seoul, South Korea.
Hwang JI; Graduate School of Medicine, Korea University, Seoul, South Korea.
Seong JK; Department of Anatomy and Cell Biology, College of Veterinary Medicine, Seoul National University, Seoul, South Korea.
Yoon YS; Korea Mouse Phenotyping Center, College of Veterinary Medicine, Seoul National University, Seoul, South Korea.
Oh SH; Department of Anatomy and Cell Biology, College of Veterinary Medicine, Seoul National University, Seoul, South Korea.

J Cell Mol Med ; 26(20): 5122-5134, 2022 10.

Article en En | MEDLINE | ID: mdl-36071453

Asunto(s)

Moléculas de Adhesión Celular Neuronal; Galactosamina; Fallo Hepático Agudo; Factores de Crecimiento Nervioso; Animales; Apoptosis; Caspasas/metabolismo; Moléculas de Adhesión Celular Neuronal/genética; Moléculas de Adhesión Celular Neuronal/metabolismo; Células Endoteliales/metabolismo; Hepatocitos/metabolismo; Humanos; Lipopolisacáridos; Hígado/metabolismo; Fallo Hepático Agudo/inducido químicamente; Fallo Hepático Agudo/genética; Fallo Hepático Agudo/metabolismo; Ratones; Ratones Noqueados; Factores de Crecimiento Nervioso/genética; Factores de Crecimiento Nervioso/metabolismo; Receptores Tipo I de Factores de Necrosis Tumoral; Factor de Necrosis Tumoral alfa/genética; Factor de Necrosis Tumoral alfa/metabolismo

Palabras clave

D-galactosamine; KO mouse; LPS; Ninjurin1; TNFR1; cell death

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Moléculas de Adhesión Celular Neuronal / Fallo Hepático Agudo / Galactosamina / Factores de Crecimiento Nervioso Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: J Cell Mol Med Asunto de la revista: BIOLOGIA MOLECULAR Año: 2022 Tipo del documento: Article País de afiliación: Corea del Sur

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