Age-related decline in the resistance of mice to bacterial infection and in LPS/TLR4 pathway-dependent neutrophil responses.

Hornigold, Kirsti; Chu, Julia Y; Chetwynd, Stephen A; Machin, Polly A; Crossland, Laraine; Pantarelli, Chiara; Anderson, Karen E; Hawkins, Phillip T; Segonds-Pichon, Anne; Oxley, David; Welch, Heidi C E

Hornigold, Kirsti; Chu, Julia Y; Chetwynd, Stephen A; Machin, Polly A; Crossland, Laraine; Pantarelli, Chiara; Anderson, Karen E; Hawkins, Phillip T; Segonds-Pichon, Anne; Oxley, David; Welch, Heidi C E.

Afiliación

Hornigold K; Signalling Programme, The Babraham Institute, Cambridge, United Kingdom.
Chu JY; Signalling Programme, The Babraham Institute, Cambridge, United Kingdom.
Chetwynd SA; Signalling Programme, The Babraham Institute, Cambridge, United Kingdom.
Machin PA; Signalling Programme, The Babraham Institute, Cambridge, United Kingdom.
Crossland L; Signalling Programme, The Babraham Institute, Cambridge, United Kingdom.
Pantarelli C; Signalling Programme, The Babraham Institute, Cambridge, United Kingdom.
Anderson KE; Signalling Programme, The Babraham Institute, Cambridge, United Kingdom.
Hawkins PT; Signalling Programme, The Babraham Institute, Cambridge, United Kingdom.
Segonds-Pichon A; Bioinformatics Facility, The Babraham Institute, Cambridge, United Kingdom.
Oxley D; Proteomics Facility, The Babraham Institute, Cambridge, United Kingdom.
Welch HCE; Signalling Programme, The Babraham Institute, Cambridge, United Kingdom.

Front Immunol ; 13: 888415, 2022.

Article en En | MEDLINE | ID: mdl-36090969

Asunto(s)

Infecciones Bacterianas; Peritonitis; Animales; Infecciones Bacterianas/metabolismo; Escherichia coli/metabolismo; Factor Estimulante de Colonias de Granulocitos y Macrófagos/metabolismo; Humanos; Lipopolisacáridos/farmacología; Ratones; Neutrófilos/metabolismo; Peritonitis/metabolismo; Staphylococcus aureus/metabolismo; Receptor Toll-Like 4/metabolismo; Receptores Toll-Like/metabolismo; Factor de Necrosis Tumoral alfa/metabolismo

Palabras clave

NETs; ROS; TLR4; aging; degranulation; neutrophils; phagocytosis; proteomics

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Peritonitis / Infecciones Bacterianas Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Front Immunol Año: 2022 Tipo del documento: Article País de afiliación: Reino Unido

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