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Epigenetic activation of the FLT3 gene by ZNF384 fusion confers a therapeutic susceptibility in acute lymphoblastic leukemia.
Zhao, Xujie; Wang, Ping; Diedrich, Jonathan D; Smart, Brandon; Reyes, Noemi; Yoshimura, Satoshi; Zhang, Jingliao; Yang, Wentao; Barnett, Kelly; Xu, Beisi; Li, Zhenhua; Huang, Xin; Yu, Jiyang; Crews, Kristine; Yeoh, Allen Eng Juh; Konopleva, Marina; Wei, Chia-Lin; Pui, Ching-Hon; Savic, Daniel; Yang, Jun J.
Afiliación
  • Zhao X; Department of Pharmacy and Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, TN, USA.
  • Wang P; The Jackson Laboratory for Genomic Medicine, Farmington, CT, USA.
  • Diedrich JD; Department of Pharmacy and Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, TN, USA.
  • Smart B; Department of Pharmacy and Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, TN, USA.
  • Reyes N; Department of Pharmacy and Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, TN, USA.
  • Yoshimura S; Department of Pharmacy and Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, TN, USA.
  • Zhang J; Department of Pharmacy and Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, TN, USA.
  • Yang W; Department of Pharmacy and Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, TN, USA.
  • Barnett K; Department of Pharmacy and Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, TN, USA.
  • Xu B; Center for Applied Bioinformatics, St. Jude Children's Research Hospital, Memphis, TN, USA.
  • Li Z; Department of Pharmacy and Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, TN, USA.
  • Huang X; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN, USA.
  • Yu J; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN, USA.
  • Crews K; Department of Pharmacy and Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, TN, USA.
  • Yeoh AEJ; Department of Pediatrics, National University of Singapore, Singapore, Singapore.
  • Konopleva M; Departments of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Wei CL; The Jackson Laboratory for Genomic Medicine, Farmington, CT, USA.
  • Pui CH; Department of Oncology, St. Jude Children's Research Hospital, Memphis, TN, USA.
  • Savic D; Department of Pharmacy and Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, TN, USA.
  • Yang JJ; Department of Pharmacy and Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, TN, USA. jun.yang@stjude.org.
Nat Commun ; 13(1): 5401, 2022 09 14.
Article en En | MEDLINE | ID: mdl-36104354

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Transactivadores / Leucemia-Linfoma Linfoblástico de Células Precursoras Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Transactivadores / Leucemia-Linfoma Linfoblástico de Células Precursoras Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos