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A small molecule antagonist of SMN disrupts the interaction between SMN and RNAP II.
Liu, Yanli; Iqbal, Aman; Li, Weiguo; Ni, Zuyao; Wang, Yalong; Ramprasad, Jurupula; Abraham, Karan Joshua; Zhang, Mengmeng; Zhao, Dorothy Yanling; Qin, Su; Loppnau, Peter; Jiang, Honglv; Guo, Xinghua; Brown, Peter J; Zhen, Xuechu; Xu, Guoqiang; Mekhail, Karim; Ji, Xingyue; Bedford, Mark T; Greenblatt, Jack F; Min, Jinrong.
Afiliación
  • Liu Y; Jiangsu Key Laboratory of Neuropsychiatric Diseases and College of Pharmaceutical Sciences, Soochow University, Suzhou, Jiangsu, China. ylliu18@suda.edu.cn.
  • Iqbal A; Hubei Key Laboratory of Genetic Regulation and Integrative Biology, School of Life Sciences, Central China Normal University, Wuhan, Hubei, China. ylliu18@suda.edu.cn.
  • Li W; Structural Genomics Consortium, University of Toronto, Toronto, ON, Canada. ylliu18@suda.edu.cn.
  • Ni Z; Structural Genomics Consortium, University of Toronto, Toronto, ON, Canada.
  • Wang Y; Hubei Key Laboratory of Genetic Regulation and Integrative Biology, School of Life Sciences, Central China Normal University, Wuhan, Hubei, China.
  • Ramprasad J; Structural Genomics Consortium, University of Toronto, Toronto, ON, Canada.
  • Abraham KJ; Donnelly Centre, University of Toronto, Toronto, ON, Canada.
  • Zhang M; Department of Epigenetics and Molecular Carcinogenesis, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Zhao DY; Jiangsu Key Laboratory of Neuropsychiatric Diseases and College of Pharmaceutical Sciences, Soochow University, Suzhou, Jiangsu, China.
  • Qin S; Department of Laboratory Medicine and Pathobiology, Faculty of Medicine, University of Toronto, Toronto, ON, Canada.
  • Loppnau P; Jiangsu Key Laboratory of Neuropsychiatric Diseases and College of Pharmaceutical Sciences, Soochow University, Suzhou, Jiangsu, China.
  • Jiang H; Donnelly Centre, University of Toronto, Toronto, ON, Canada.
  • Guo X; Structural Genomics Consortium, University of Toronto, Toronto, ON, Canada.
  • Brown PJ; Life Science Research Center, Southern University of Science and Technology, Shenzhen, Guangdong, China.
  • Zhen X; Structural Genomics Consortium, University of Toronto, Toronto, ON, Canada.
  • Xu G; Jiangsu Key Laboratory of Neuropsychiatric Diseases and College of Pharmaceutical Sciences, Soochow University, Suzhou, Jiangsu, China.
  • Mekhail K; Donnelly Centre, University of Toronto, Toronto, ON, Canada.
  • Ji X; Structural Genomics Consortium, University of Toronto, Toronto, ON, Canada.
  • Bedford MT; Jiangsu Key Laboratory of Neuropsychiatric Diseases and College of Pharmaceutical Sciences, Soochow University, Suzhou, Jiangsu, China.
  • Greenblatt JF; Jiangsu Key Laboratory of Neuropsychiatric Diseases and College of Pharmaceutical Sciences, Soochow University, Suzhou, Jiangsu, China.
  • Min J; Department of Laboratory Medicine and Pathobiology, Faculty of Medicine, University of Toronto, Toronto, ON, Canada.
Nat Commun ; 13(1): 5453, 2022 09 16.
Article en En | MEDLINE | ID: mdl-36114190
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: ARN Polimerasa II / Proteínas del Complejo SMN Límite: Humans Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2022 Tipo del documento: Article País de afiliación: China
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: ARN Polimerasa II / Proteínas del Complejo SMN Límite: Humans Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2022 Tipo del documento: Article País de afiliación: China