Zygo-Albuside A: New Saponin from <i>Zygophyllum album</i> L. with Significant Antioxidant, Anti-Inflammatory and Antiapoptotic Effects against Methotrexate-Induced Testicular Damage.

Abdelhameed, Reda F A; Fattah, Shaimaa A; Mehanna, Eman T; Hal, Dina M; Mosaad, Sarah M; Abdel-Kader, Maged S; Ibrahim, Amany K; Ahmed, Safwat A; Badr, Jihan M; Eltamany, Enas E

Zygo-Albuside A: New Saponin from Zygophyllum album L. with Significant Antioxidant, Anti-Inflammatory and Antiapoptotic Effects against Methotrexate-Induced Testicular Damage.

Abdelhameed, Reda F A; Fattah, Shaimaa A; Mehanna, Eman T; Hal, Dina M; Mosaad, Sarah M; Abdel-Kader, Maged S; Ibrahim, Amany K; Ahmed, Safwat A; Badr, Jihan M; Eltamany, Enas E.

Afiliación

Abdelhameed RFA; Department of Pharmacognosy, Faculty of Pharmacy, Suez Canal University, Ismailia 41522, Egypt.
Fattah SA; Department of Pharmacognosy, Faculty of Pharmacy, Galala University, New Galala 43713, Egypt.
Mehanna ET; Department of Biochemistry, Faculty of Pharmacy, Suez Canal University, Ismailia 41522, Egypt.
Hal DM; Department of Biochemistry, Faculty of Pharmacy, Suez Canal University, Ismailia 41522, Egypt.
Mosaad SM; Department of Pharmacognosy, Faculty of Pharmacy, Suez Canal University, Ismailia 41522, Egypt.
Abdel-Kader MS; Division of Pharmacology and Therapeutics, General Authority of Healthcare, Ismailia 41522, Egypt.
Ibrahim AK; Department of Pharmacognosy, College of Pharmacy, Prince Sattam Bin Abdulaziz University, Al-Kharj 11942, Saudi Arabia.
Ahmed SA; Department of Pharmacognosy, Faculty of Pharmacy, Alexandria University, Alexandria 21215, Egypt.
Badr JM; Department of Pharmacognosy, Faculty of Pharmacy, Suez Canal University, Ismailia 41522, Egypt.
Eltamany EE; Department of Pharmacognosy, Faculty of Pharmacy, Suez Canal University, Ismailia 41522, Egypt.

Int J Mol Sci ; 23(18)2022 Sep 16.

Article en En | MEDLINE | ID: mdl-36142712

Asunto(s)

MicroARNs; Saponinas; Zygophyllum; Animales; Antiinflamatorios/farmacología; Antioxidantes/metabolismo; Antioxidantes/farmacología; Catalasa/metabolismo; Dimetilsulfóxido/farmacología; Interleucina-6/metabolismo; Malondialdehído/metabolismo; Metotrexato/farmacología; MicroARNs/metabolismo; FN-kappa B/metabolismo; Estrés Oxidativo; Extractos Vegetales/química; ARN Mensajero/metabolismo; Rutina/metabolismo; Rutina/farmacología; Saponinas/metabolismo; Saponinas/farmacología; Superóxido Dismutasa/metabolismo; Testículo/metabolismo; Testosterona/metabolismo; Factor de Necrosis Tumoral alfa/metabolismo; Proteína p53 Supresora de Tumor/metabolismo; Agua/metabolismo; Proteína X Asociada a bcl-2/metabolismo

Palabras clave

Zygophyllum album L.; antiapoptotic; antioxidant activity; saponins; testicular damage

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Saponinas / Zygophyllum / MicroARNs Límite: Animals Idioma: En Revista: Int J Mol Sci Año: 2022 Tipo del documento: Article País de afiliación: Egipto

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