Neuroprotective effects of Lasmiditan and Sumatriptan in an experimental model of post-stroke seizure in mice: Higher effects with concurrent opioid receptors or K<sub>ATP</sub> channels inhibitors.

Shayan, Maryam; Eslami, Faezeh; Amanlou, Arash; Solaimanian, Shahabaddin; Rahimi, Nastaran; Rashidian, Amir; Ejtemaei-Mehr, Shahram; Ghasemi, Mehdi; Dehpour, Ahmad-Reza

Neuroprotective effects of Lasmiditan and Sumatriptan in an experimental model of post-stroke seizure in mice: Higher effects with concurrent opioid receptors or K_ATP channels inhibitors.

Shayan, Maryam; Eslami, Faezeh; Amanlou, Arash; Solaimanian, Shahabaddin; Rahimi, Nastaran; Rashidian, Amir; Ejtemaei-Mehr, Shahram; Ghasemi, Mehdi; Dehpour, Ahmad-Reza.

Afiliación

Shayan M; Experimental Medicine Research Center, Tehran University of Medical Sciences, Tehran, Iran; Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Eslami F; Experimental Medicine Research Center, Tehran University of Medical Sciences, Tehran, Iran; Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Amanlou A; Experimental Medicine Research Center, Tehran University of Medical Sciences, Tehran, Iran; Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Solaimanian S; Experimental Medicine Research Center, Tehran University of Medical Sciences, Tehran, Iran; Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Rahimi N; Experimental Medicine Research Center, Tehran University of Medical Sciences, Tehran, Iran; Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Rashidian A; Experimental Medicine Research Center, Tehran University of Medical Sciences, Tehran, Iran; Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Ejtemaei-Mehr S; Experimental Medicine Research Center, Tehran University of Medical Sciences, Tehran, Iran; Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Ghasemi M; Department of Neurology, University of Massachusetts Chan Medical School, Worcester, MA 01655, USA. Electronic address: mehdi.ghasemi@umassmemorial.org.
Dehpour AR; Experimental Medicine Research Center, Tehran University of Medical Sciences, Tehran, Iran; Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran. Electronic address: dehpour@yahoo.com.

Toxicol Appl Pharmacol ; 454: 116254, 2022 11 01.

Article en En | MEDLINE | ID: mdl-36155770

Asunto(s)

Fármacos Neuroprotectores; Accidente Cerebrovascular; Adenosina Trifosfato; Animales; Anticonvulsivantes/farmacología; Benzamidas; Modelos Animales de Enfermedad; Relación Dosis-Respuesta a Droga; Gliburida/farmacología; Gliburida/uso terapéutico; Ratones; Modelos Teóricos; Naltrexona/farmacología; Antagonistas de Narcóticos/farmacología; Pentilenotetrazol; Piperidinas; Bloqueadores de los Canales de Potasio; Canales de Potasio/metabolismo; Piridinas; Receptores Opioides; Convulsiones/tratamiento farmacológico; Convulsiones/etiología; Convulsiones/prevención & control; Accidente Cerebrovascular/tratamiento farmacológico; Sumatriptán; Factor de Necrosis Tumoral alfa; Proteína X Asociada a bcl-2

Palabras clave

K(ATP) channels; Lasmiditan; Mice; Opioid receptors; Seizure; Stroke; Sumatriptan

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Fármacos Neuroprotectores / Accidente Cerebrovascular Tipo de estudio: Etiology_studies / Prognostic_studies Límite: Animals Idioma: En Revista: Toxicol Appl Pharmacol Año: 2022 Tipo del documento: Article País de afiliación: Irán

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