Evaluation of Small-Molecule HDAC Inhibitors Through In Vitro and In Cellulo Approaches.

Nawar, Nabanita; Garcha, Harsimran Kaur; Sedighi, Abootaleb; de Araujo, Elvin D; Gunning, Patrick T

Nawar, Nabanita; Garcha, Harsimran Kaur; Sedighi, Abootaleb; de Araujo, Elvin D; Gunning, Patrick T.

Afiliación

Nawar N; Department of Chemical and Physical Sciences, University of Toronto Mississauga, Mississauga, ON, Canada.
Garcha HK; Department of Chemistry, University of Toronto, Toronto, ON, Canada.
Sedighi A; Department of Chemical and Physical Sciences, University of Toronto Mississauga, Mississauga, ON, Canada.
de Araujo ED; Department of Chemistry, University of Toronto, Toronto, ON, Canada.
Gunning PT; Department of Chemical and Physical Sciences, University of Toronto Mississauga, Mississauga, ON, Canada.

Methods Mol Biol ; 2589: 157-177, 2023.

Article en En | MEDLINE | ID: mdl-36255624

Asunto(s)

Inhibidores de Histona Desacetilasas; Histona Desacetilasas; Inhibidores de Histona Desacetilasas/farmacología; Inhibidores de Histona Desacetilasas/química; Histona Desacetilasas/metabolismo; Isoformas de Proteínas/metabolismo; Membranas Artificiales; Lípidos

Palabras clave

Cytotoxicity; HDAC inhibitor; PAMPA; Selectivity; Stability; Western blotting; Whole blood

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Inhibidores de Histona Desacetilasas / Histona Desacetilasas Idioma: En Revista: Methods Mol Biol Asunto de la revista: BIOLOGIA MOLECULAR Año: 2023 Tipo del documento: Article País de afiliación: Canadá

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