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Therapeutic gene editing of T cells to correct CTLA-4 insufficiency.
Fox, Thomas Andrew; Houghton, Benjamin Christopher; Petersone, Lina; Waters, Erin; Edner, Natalie Mona; McKenna, Alex; Preham, Olivier; Hinze, Claudia; Williams, Cayman; de Albuquerque, Adriana Silva; Kennedy, Alan; Pesenacker, Anne Maria; Genovese, Pietro; Walker, Lucy Sarah Kate; Burns, Siobhan Oisin; Sansom, David Michael; Booth, Claire; Morris, Emma Catherine.
Afiliación
  • Fox TA; UCL Institute of Immunity and Transplantation, University College London, London, NW3 2PP, UK.
  • Houghton BC; Department of Haematology, University College London NHS Foundation Trust, London, NW1 2BU UK.
  • Petersone L; UCL Great Ormond Street Institute of Child Health, UCL, London WC1N 1EH, UK.
  • Waters E; UCL Great Ormond Street Institute of Child Health, UCL, London WC1N 1EH, UK.
  • Edner NM; UCL Institute of Immunity and Transplantation, University College London, London, NW3 2PP, UK.
  • McKenna A; UCL Institute of Immunity and Transplantation, University College London, London, NW3 2PP, UK.
  • Preham O; UCL Institute of Immunity and Transplantation, University College London, London, NW3 2PP, UK.
  • Hinze C; UCL Institute of Immunity and Transplantation, University College London, London, NW3 2PP, UK.
  • Williams C; UCL Institute of Immunity and Transplantation, University College London, London, NW3 2PP, UK.
  • de Albuquerque AS; UCL Institute of Immunity and Transplantation, University College London, London, NW3 2PP, UK.
  • Kennedy A; UCL Institute of Immunity and Transplantation, University College London, London, NW3 2PP, UK.
  • Pesenacker AM; UCL Institute of Immunity and Transplantation, University College London, London, NW3 2PP, UK.
  • Genovese P; University College London Hospital, National Institute for Health and Care Research Biomedical Research Centre, London W1T 7DN, UK.
  • Walker LSK; UCL Institute of Immunity and Transplantation, University College London, London, NW3 2PP, UK.
  • Burns SO; UCL Institute of Immunity and Transplantation, University College London, London, NW3 2PP, UK.
  • Sansom DM; Dana-Farber/Boston Children's Cancer and Blood Disorder Center, Boston, MA 02115, USA.
  • Booth C; UCL Institute of Immunity and Transplantation, University College London, London, NW3 2PP, UK.
  • Morris EC; UCL Institute of Immunity and Transplantation, University College London, London, NW3 2PP, UK.
Sci Transl Med ; 14(668): eabn5811, 2022 10 26.
Article en En | MEDLINE | ID: mdl-36288278

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Activación de Linfocitos / Linfocitos T Límite: Animals / Humans Idioma: En Revista: Sci Transl Med Asunto de la revista: CIENCIA / MEDICINA Año: 2022 Tipo del documento: Article País de afiliación: Reino Unido

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Activación de Linfocitos / Linfocitos T Límite: Animals / Humans Idioma: En Revista: Sci Transl Med Asunto de la revista: CIENCIA / MEDICINA Año: 2022 Tipo del documento: Article País de afiliación: Reino Unido