Influence of dietary protein on serum phosphorous levels in peritoneal dialysis patients with different initial transport function.
Ren Fail
; 44(1): 2085-2092, 2022 Dec.
Article
en En
| MEDLINE
| ID: mdl-36426736
ABSTRACT
INTRODUCTION:
This cross-sectional study investigated the influence of dietary protein intake (DPI) on serum phosphate levels in peritoneal dialysis (PD) patients and determined the DPI cutoff required to prevent hyperphosphatemia.METHODS:
A total of 504 PD patients were categorized into fast (4 h dialysate/plasma [D/P] creatinine clearance ≥0.65) or slow (<0.65) peritoneal transporters. Serum phosphorus and peritoneal solute clearance were compared between the groups with different DPI.RESULTS:
The fast peritoneal transporters (n = 233) were older, had lower serum albumin and phosphorus levels, and had higher peritoneal phosphorus clearance (all p < 0.001). Among the slow transporters (n = 271), serum phosphorus levels were significantly higher among patients with DPI > 1.0 g/kg/d (p < 0.001). High DPI only increased the hyperphosphatemia risk in slow transporters (not in high transporters). DPI ≥1.026 g increased the hyperphosphatemia risk in those patients (area under the curve 0.66, p = 0.001).CONCLUSION:
High DPI increases the hyperphosphatemia risk in PD patients with slower peritoneal transport function.Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Diálisis Peritoneal
/
Hiperfosfatemia
Tipo de estudio:
Observational_studies
/
Prevalence_studies
/
Prognostic_studies
/
Risk_factors_studies
Límite:
Humans
Idioma:
En
Revista:
Ren Fail
Asunto de la revista:
NEFROLOGIA
Año:
2022
Tipo del documento:
Article
País de afiliación:
China