Senescence-associated secretory proteins induced in lung adenocarcinoma by extended treatment with dexamethasone enhance migration and activation of lymphocytes.

Parajuli, Prahlad; Rosati, Rayna; Mamdani, Hirva; Wright, Robert E; Hussain, Zahin; Naeem, Aroma; Dzinic, Sijana; Polin, Lisa; Gavande, Navnath S; Ratnam, Manohar

Parajuli, Prahlad; Rosati, Rayna; Mamdani, Hirva; Wright, Robert E; Hussain, Zahin; Naeem, Aroma; Dzinic, Sijana; Polin, Lisa; Gavande, Navnath S; Ratnam, Manohar.

Afiliación

Parajuli P; Department of Pharmaceutical Sciences, Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, Detroit, MI, 48201, USA. pparajuli@wayne.edu.
Rosati R; Molecular Therapeutics Program, Barbara Ann Karmanos Cancer Institute, Detroit, MI, 48201, USA. pparajuli@wayne.edu.
Mamdani H; Department of Oncology, Wayne State University School of Medicine, Detroit, MI, 48201, USA.
Wright RE; Department of Oncology, Wayne State University School of Medicine, Detroit, MI, 48201, USA.
Hussain Z; Department of Pharmaceutical Sciences, Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, Detroit, MI, 48201, USA.
Naeem A; Department of Pharmaceutical Sciences, Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, Detroit, MI, 48201, USA.
Dzinic S; Department of Pharmaceutical Sciences, Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, Detroit, MI, 48201, USA.
Polin L; Department of Oncology, Wayne State University School of Medicine, Detroit, MI, 48201, USA.
Gavande NS; Department of Oncology, Wayne State University School of Medicine, Detroit, MI, 48201, USA.
Ratnam M; Department of Pharmaceutical Sciences, Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, Detroit, MI, 48201, USA.

Cancer Immunol Immunother ; 72(5): 1273-1284, 2023 May.

Article en En | MEDLINE | ID: mdl-36434273

Asunto(s)

Adenocarcinoma del Pulmón; Neoplasias Pulmonares; Humanos; Animales; Ratones; Dexametasona/farmacología; Adenocarcinoma del Pulmón/tratamiento farmacológico; Neoplasias Pulmonares/metabolismo; Células Asesinas Naturales/metabolismo; Senescencia Celular/genética

Palabras clave

Chemokines; Glucocorticoid receptor; Humanized NSG mice; Lung adenocarcinoma; NKG2D; Tumor senescence

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Adenocarcinoma del Pulmón / Neoplasias Pulmonares Tipo de estudio: Risk_factors_studies Límite: Animals / Humans Idioma: En Revista: Cancer Immunol Immunother Asunto de la revista: ALERGIA E IMUNOLOGIA / NEOPLASIAS / TERAPEUTICA Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos

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