Limb-girdle muscular dystrophy type 2B causes HDL-C abnormalities in patients and statin-resistant muscle wasting in dysferlin-deficient mice.

White, Zoe; Sun, Zeren; Sauge, Elodie; Cox, Dan; Donen, Graham; Pechkovsky, Dmitri; Straub, Volker; Francis, Gordon A; Bernatchez, Pascal

White, Zoe; Sun, Zeren; Sauge, Elodie; Cox, Dan; Donen, Graham; Pechkovsky, Dmitri; Straub, Volker; Francis, Gordon A; Bernatchez, Pascal.

Afiliación

White Z; Department of Anesthesiology, Pharmacology & Therapeutics, University of British Columbia (UBC), 217-2176 Health Sciences Mall, Vancouver, BC, V6T 1Z3, Canada.
Sun Z; UBC Centre for Heart Lung Innovation, St. Paul's Hospital, Vancouver, Canada.
Sauge E; Department of Anesthesiology, Pharmacology & Therapeutics, University of British Columbia (UBC), 217-2176 Health Sciences Mall, Vancouver, BC, V6T 1Z3, Canada.
Cox D; UBC Centre for Heart Lung Innovation, St. Paul's Hospital, Vancouver, Canada.
Donen G; Department of Anesthesiology, Pharmacology & Therapeutics, University of British Columbia (UBC), 217-2176 Health Sciences Mall, Vancouver, BC, V6T 1Z3, Canada.
Pechkovsky D; UBC Centre for Heart Lung Innovation, St. Paul's Hospital, Vancouver, Canada.
Straub V; Newcastle University Translational and Clinical Research Institute, Newcastle upon Tyne, UK.
Francis GA; Department of Anesthesiology, Pharmacology & Therapeutics, University of British Columbia (UBC), 217-2176 Health Sciences Mall, Vancouver, BC, V6T 1Z3, Canada.
Bernatchez P; UBC Centre for Heart Lung Innovation, St. Paul's Hospital, Vancouver, Canada.

Skelet Muscle ; 12(1): 25, 2022 11 29.

Article en En | MEDLINE | ID: mdl-36447272

Asunto(s)

Inhibidores de Hidroximetilglutaril-CoA Reductasas; Distrofia Muscular de Cinturas; Ratones; Animales; Disferlina/genética; Inhibidores de Hidroximetilglutaril-CoA Reductasas/farmacología; Inhibidores de Hidroximetilglutaril-CoA Reductasas/uso terapéutico; Distrofina; HDL-Colesterol; Distrofia Muscular de Cinturas/tratamiento farmacológico; Distrofia Muscular de Cinturas/genética; Atrofia Muscular; Simvastatina/farmacología; Simvastatina/uso terapéutico

Palabras clave

Cholesterol; Dysferlin; Dyslipidemia; Simvastatin

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Inhibidores de Hidroximetilglutaril-CoA Reductasas / Distrofia Muscular de Cinturas Tipo de estudio: Etiology_studies / Risk_factors_studies Límite: Animals Idioma: En Revista: Skelet Muscle Año: 2022 Tipo del documento: Article País de afiliación: Canadá

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