The design of a randomized, placebo-controlled, dose-ranging trial to investigate the efficacy and safety of the ADAMTS-5 inhibitor S201086/GLPG1972 in knee osteoarthritis.

Imbert, Olivier; Deckx, Henri; Bernard, Katy; van der Aar, Ellen; Pueyo, Maria; Saeed, Nadeem; Fuerst, Thomas; Wirth, Wolfgang; Conaghan, Philip G; Eckstein, Felix

Imbert, Olivier; Deckx, Henri; Bernard, Katy; van der Aar, Ellen; Pueyo, Maria; Saeed, Nadeem; Fuerst, Thomas; Wirth, Wolfgang; Conaghan, Philip G; Eckstein, Felix.

Afiliación

Imbert O; Institut de Recherches Internationales Servier (IRIS), Suresnes, France.
Deckx H; Galapagos NV, Mechelen, Belgium.
Bernard K; Institut de Recherches Internationales Servier (IRIS), Suresnes, France.
van der Aar E; Galapagos NV, Mechelen, Belgium.
Pueyo M; Institut de Recherches Internationales Servier (IRIS), Suresnes, France.
Saeed N; Bioclinica, London, UK.
Fuerst T; Bioclinica, Newark, CA, USA.
Wirth W; Chondrometrics GmbH, Ainring, Germany.
Conaghan PG; Institute of Anatomy and Cell Biology and Ludwig Boltzmann Institute for Arthritis and Rehabilitation (LBIAR), Paracelsus Medical University, Salzburg, Austria.
Eckstein F; Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds and NIHR Leeds Biomedical Research Centre, UK.

Osteoarthr Cartil Open ; 3(4): 100209, 2021 Dec.

Article en En | MEDLINE | ID: mdl-36474770

Palabras clave

ADAMTS-5 inhibitor; Cartilage; Clinical trial; Disease modification; Knee osteoarthritis; Quantitative magnetic resonance imaging

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Texto completo: 1 Banco de datos: MEDLINE Tipo de estudio: Clinical_trials Idioma: En Revista: Osteoarthr Cartil Open Año: 2021 Tipo del documento: Article País de afiliación: Francia

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