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Causal inference in medical records and complementary systems pharmacology for metformin drug repurposing towards dementia.
Charpignon, Marie-Laure; Vakulenko-Lagun, Bella; Zheng, Bang; Magdamo, Colin; Su, Bowen; Evans, Kyle; Rodriguez, Steve; Sokolov, Artem; Boswell, Sarah; Sheu, Yi-Han; Somai, Melek; Middleton, Lefkos; Hyman, Bradley T; Betensky, Rebecca A; Finkelstein, Stan N; Welsch, Roy E; Tzoulaki, Ioanna; Blacker, Deborah; Das, Sudeshna; Albers, Mark W.
Afiliación
  • Charpignon ML; Institute for Data, Systems, and Society, Massachusetts Institute of Technology, Cambridge, MA, USA.
  • Vakulenko-Lagun B; Department of Statistics, University of Haifa, Mt Carmel, Haifa, Israel.
  • Zheng B; Ageing Epidemiology Research Unit, School of Public Health, Imperial College London, London, UK.
  • Magdamo C; Department of Neurology, Massachusetts General Hospital/Harvard Medical School, Boston, MA, USA.
  • Su B; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK.
  • Evans K; Department of Neurology, Massachusetts General Hospital/Harvard Medical School, Boston, MA, USA.
  • Rodriguez S; Laboratory of Systems Pharmacology, Harvard Program in Therapeutic Science, Harvard Medical School, Boston, MA, USA.
  • Sokolov A; Department of Neurology, Massachusetts General Hospital/Harvard Medical School, Boston, MA, USA.
  • Boswell S; Laboratory of Systems Pharmacology, Harvard Program in Therapeutic Science, Harvard Medical School, Boston, MA, USA.
  • Sheu YH; Laboratory of Systems Pharmacology, Harvard Program in Therapeutic Science, Harvard Medical School, Boston, MA, USA.
  • Somai M; Laboratory of Systems Pharmacology, Harvard Program in Therapeutic Science, Harvard Medical School, Boston, MA, USA.
  • Middleton L; Department of Psychiatry, Massachusetts General Hospital/Harvard Medical School, Boston, MA, USA.
  • Hyman BT; Inception Labs, Collaborative for Health Delivery Sciences, Medical College of Wisconsin, Wauwatosa, WI, USA.
  • Betensky RA; Ageing Epidemiology Research Unit, School of Public Health, Imperial College London, London, UK.
  • Finkelstein SN; Public Health Directorate, Imperial College London NHS Healthcare Trust, London, UK.
  • Welsch RE; Department of Neurology, Massachusetts General Hospital/Harvard Medical School, Boston, MA, USA.
  • Tzoulaki I; Department of Biostatistics, School of Global Public Health, New York University, New York, NY, USA.
  • Blacker D; Institute for Data, Systems, and Society, Massachusetts Institute of Technology, Cambridge, MA, USA.
  • Das S; Division of Clinical Informatics, Beth Israel Deaconess Medical Center, Boston, MA, USA.
  • Albers MW; Institute for Data, Systems, and Society, Massachusetts Institute of Technology, Cambridge, MA, USA.
Nat Commun ; 13(1): 7652, 2022 Dec 10.
Article en En | MEDLINE | ID: mdl-36496454
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Demencia / Diabetes Mellitus Tipo 2 / Metformina Tipo de estudio: Etiology_studies / Observational_studies Límite: Humans Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Demencia / Diabetes Mellitus Tipo 2 / Metformina Tipo de estudio: Etiology_studies / Observational_studies Límite: Humans Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos