SPOP loss of function protects against tauopathy.

Eck, Randall J; Kow, Rebecca L; Black, Aristide H; Liachko, Nicole F; Kraemer, Brian C

Eck, Randall J; Kow, Rebecca L; Black, Aristide H; Liachko, Nicole F; Kraemer, Brian C.

Afiliación

Eck RJ; Graduate Program in Neuroscience, University of Washington, Seattle, WA 98195.
Kow RL; Division of Gerontology and Geriatric Medicine, Department of Medicine, University of Washington, Seattle, WA 98104.
Black AH; Division of Gerontology and Geriatric Medicine, Department of Medicine, University of Washington, Seattle, WA 98104.
Liachko NF; Geriatrics Research Education and Clinical Center, Veterans Affairs Puget Sound Health Care System, Seattle, WA 98108.
Kraemer BC; Geriatrics Research Education and Clinical Center, Veterans Affairs Puget Sound Health Care System, Seattle, WA 98108.

Proc Natl Acad Sci U S A ; 120(1): e2207250120, 2023 01 03.

Article en En | MEDLINE | ID: mdl-36574656

Asunto(s)

Enfermedad de Alzheimer; Proteínas de Caenorhabditis elegans; Tauopatías; Animales; Caenorhabditis elegans/genética; Caenorhabditis elegans/metabolismo; Tauopatías/metabolismo; Proteínas tau/genética; Proteínas tau/metabolismo; Proteínas Nucleares/genética; Proteínas Nucleares/metabolismo; Animales Modificados Genéticamente; Enfermedad de Alzheimer/metabolismo; Modelos Animales de Enfermedad; Mamíferos/metabolismo; Proteínas de Caenorhabditis elegans/genética; Proteínas de Caenorhabditis elegans/metabolismo; Proteínas de Unión a Poli(A)/metabolismo

Palabras clave

Alzheimer's disease; C. elegans; neurodegeneration; tau; tauopathy

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Tauopatías / Proteínas de Caenorhabditis elegans / Enfermedad de Alzheimer Límite: Animals Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2023 Tipo del documento: Article

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