Antimicrobial and antibiofilm activity of isoorientin against carbapenem non-sensitive Escherichia coli from raw milk of goats.
J Anim Sci
; 1012023 Jan 03.
Article
en En
| MEDLINE
| ID: mdl-36762933
Escherichia coli (E. coli) has been the major foodborne bacteria that can cause diarrhea, gastroenteritis, and some complications, and also used as fecal bacteria pollution indicator in food. Carbapenems are considered as the last resort to life-threatening E. coli infections. We evaluated the antimicrobial and antibiofilm effects of isoorientin against biofilm-forming carbapenem non-sensitive E. coli from raw milk of goats, and explored its molecular mechanisms. This study firstly demonstrated the potential antimicrobial and antibiofilm properties of isoorientin against the carbapenem non-sensitive E. coli for the first time, and it has the properties of inhibiting the biofilm formation and destroying the preformed biofilms. Therefore, isoorientin is a promising biofilm inhibitor for curtailing drug resistant foodborne pathogens, and this study could provide a scientific basis for its practical application of isoorientin.
Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Carbapenémicos
/
Antiinfecciosos
Tipo de estudio:
Diagnostic_studies
Límite:
Animals
Idioma:
En
Revista:
J Anim Sci
Año:
2023
Tipo del documento:
Article
País de afiliación:
China