Disruption of mitochondrial oxidative phosphorylation by chidamide eradicates leukemic cells in AML.

Wang, Jun-Dan; Xu, Jue-Qiong; Long, Zi-Jie; Weng, Jian-Yu

Wang, Jun-Dan; Xu, Jue-Qiong; Long, Zi-Jie; Weng, Jian-Yu.

Afiliación

Wang JD; School of Medicine, South China University of Technology, Guangzhou, China.
Xu JQ; Department of Hematology, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China.
Long ZJ; Department of Hematology, The Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Weng JY; Department of Hematology, The Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.

Clin Transl Oncol ; 25(6): 1805-1820, 2023 Jun.

Article en En | MEDLINE | ID: mdl-36899123

Asunto(s)

Leucemia Mieloide Aguda; Animales; Ratones; Leucemia Mieloide Aguda/tratamiento farmacológico; Fosforilación Oxidativa; Aminopiridinas/farmacología; Benzamidas; Apoptosis; Línea Celular Tumoral

Palabras clave

Acute myeloid leukemia; Chidamide; HDAC; Mitochondria; OXPHOS

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Leucemia Mieloide Aguda Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Clin Transl Oncol Año: 2023 Tipo del documento: Article País de afiliación: China

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