Evaluation of BAYESIL for automated annotation of 1H NMR data using limited sample volumes: application to African elephant serum.
Metabolomics
; 19(4): 31, 2023 03 30.
Article
en En
| MEDLINE
| ID: mdl-36995481
ABSTRACT
INTRODUCTION:
Technological advancements enabled the analyses of limited sample volumes on 1H NMR. Manual spectral profiling of the data is, however, complex, and timely.OBJECTIVE:
To evaluate the performance of BAYESIL for automated identification and quantification of 1H NMR spectra of limited volume samples.METHOD:
Aliquots of a pooled African elephant serum sample were analyzed using standard and reduced volumes. Performance was evaluated on confidence scores, non-detects and laboratory CV.RESULTS:
Of the 47 compounds detected, 28 had favorable performances. The approach could differentiate samples based on biological variation.CONCLUSIONS:
BAYESIL is valuable for limited sample 1H NMR data analyses.Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Elefantes
Tipo de estudio:
Prognostic_studies
Límite:
Animals
Idioma:
En
Revista:
Metabolomics
Año:
2023
Tipo del documento:
Article
País de afiliación:
Sudáfrica