Direct Alkylation of Quinoxalinones with Boracene-Based Alkylborate under Visible Light Irradiation.
J Org Chem
; 88(9): 6218-6226, 2023 May 05.
Article
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| MEDLINE
| ID: mdl-37043452
ABSTRACT
An efficient synthesis of a variety of 3-alkyl quinoxalinones via C-H direct alkylation by photoredox catalysis between quinoxalinones and alkylborates is reported. A range of quinoxalinones was tolerated well. This visible-light photocatalysis reaction allows access to structurally diverse 3-alkyl quinoxalinones in good to excellent yields. The practicality of this protocol was demonstrated by the concise synthesis of a potential bioactive nonpeptide angiotensin II receptor antagonist.
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1
Banco de datos:
MEDLINE
Tipo de estudio:
Guideline
Idioma:
En
Revista:
J Org Chem
Año:
2023
Tipo del documento:
Article
País de afiliación:
China