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Successful batch and continuous lyophilization of mRNA LNP formulations depend on cryoprotectants and ionizable lipids.
Lamoot, Alexander; Lammens, Joris; De Lombaerde, Emily; Zhong, Zifu; Gontsarik, Mark; Chen, Yong; De Beer, Thomas R M; De Geest, Bruno G.
Afiliación
  • Lamoot A; Department of Pharmaceutics, Ghent University, Ghent, Belgium. br.degeest@ugent.be.
  • Lammens J; Cancer Research Institute Ghent (CRIG), Ghent University, Ottergemsesteenweg 460, B-9000 Ghent, Belgium.
  • De Lombaerde E; Laboratory of Pharmaceutical Process Analytical Technology, Department of Pharmaceutics, Ghent University, Ottergemsesteenweg 460, B-9000 Ghent, Belgium. Thomas.DeBeer@UGent.be.
  • Zhong Z; Department of Pharmaceutics, Ghent University, Ghent, Belgium. br.degeest@ugent.be.
  • Gontsarik M; Cancer Research Institute Ghent (CRIG), Ghent University, Ottergemsesteenweg 460, B-9000 Ghent, Belgium.
  • Chen Y; Department of Pharmaceutics, Ghent University, Ghent, Belgium. br.degeest@ugent.be.
  • De Beer TRM; Cancer Research Institute Ghent (CRIG), Ghent University, Ottergemsesteenweg 460, B-9000 Ghent, Belgium.
  • De Geest BG; Department of Pharmaceutics, Ghent University, Ghent, Belgium. br.degeest@ugent.be.
Biomater Sci ; 11(12): 4327-4334, 2023 Jun 13.
Article en En | MEDLINE | ID: mdl-37073472
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Nanopartículas / Lípidos Idioma: En Revista: Biomater Sci Año: 2023 Tipo del documento: Article País de afiliación: Bélgica
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Nanopartículas / Lípidos Idioma: En Revista: Biomater Sci Año: 2023 Tipo del documento: Article País de afiliación: Bélgica