Garlic supplementation attenuates cycling exercise-induced oxidative inflammation but fails to improve time trial performance in healthy adults.
J Int Soc Sports Nutr
; 20(1): 2206809, 2023 Dec.
Article
en En
| MEDLINE
| ID: mdl-37170623
ABSTRACT
BACKGROUND:
Garlic extract has been shown to enhance antioxidant and anti-inflammation activities in humans. The present study investigated the effects of garlic supplementation on 40-km cycling time trial performance, exercise-induced oxidative stress, and inflammatory responses in healthy adults.METHODS:
Eleven healthy males were recruited to perform this single-blind crossover study. Participants were randomly assigned to either garlic (garlic extracts 1000 mg/d for 4 weeks) or placebo trials. Following 4-wks of supplementation, participants performed a 40-km cycling challenge. Total cycling performance time and respiratory exchange ratio (RER) were recorded. Blood samples were collected every 10 km to determine exercise-induced oxidative stress, inflammation, and muscle damage.RESULTS:
The 40-km cycling time trial performance was not improved following 4 weeks of garlic supplementation. However, 4-wk garlic supplementation significantly increased whole-body antioxidant capacity (total antioxidant capacity, TAC), and subsequently attenuated MDA, TNF-α, and LDH during the 40-km cycling exercise period (p < 0.05). There were no significant differences among the blood biomarkers glucose, NEFA, IL-6, UA, and CK respectively. The respiratory exchange ratio was similar between garlic and placebo trials.CONCLUSION:
Four-week oral garlic supplementation attenuates exercise-induced oxidative inflammation and muscle damage during a 40-km bout of cycling. However, it appeared that 4-wk oral garlic had no ergogenic effect on cycling performance in healthy males.Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Ajo
/
Antioxidantes
Tipo de estudio:
Clinical_trials
Límite:
Adult
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Humans
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Male
Idioma:
En
Revista:
J Int Soc Sports Nutr
Año:
2023
Tipo del documento:
Article
País de afiliación:
Taiwán