Structural basis of ELKS/Rab6B interaction and its role in vesicle capturing enhanced by liquid-liquid phase separation.

Jin, Gaowei; Lin, Leishu; Li, Kaiyue; Li, Jiashan; Yu, Cong; Wei, Zhiyi

Jin, Gaowei; Lin, Leishu; Li, Kaiyue; Li, Jiashan; Yu, Cong; Wei, Zhiyi.

Afiliación

Jin G; Brain Research Center, Southern University of Science and Technology, Shenzhen, Guangdong, China; School of Life Sciences, Southern University of Science and Technology, Shenzhen, Guangdong, China.
Lin L; Brain Research Center, Southern University of Science and Technology, Shenzhen, Guangdong, China; School of Life Sciences, Southern University of Science and Technology, Shenzhen, Guangdong, China.
Li K; Brain Research Center, Southern University of Science and Technology, Shenzhen, Guangdong, China; School of Life Sciences, Southern University of Science and Technology, Shenzhen, Guangdong, China.
Li J; Brain Research Center, Southern University of Science and Technology, Shenzhen, Guangdong, China; School of Life Sciences, Southern University of Science and Technology, Shenzhen, Guangdong, China.
Yu C; School of Life Sciences, Southern University of Science and Technology, Shenzhen, Guangdong, China; Guangdong Provincial Key Laboratory of Cell Microenvironment and Disease Research, Shenzhen Key Laboratory of Cell Microenvironment, Shenzhen, Guangdong, China. Electronic address: yuc@sustech.edu.cn.
Wei Z; Brain Research Center, Southern University of Science and Technology, Shenzhen, Guangdong, China; School of Life Sciences, Southern University of Science and Technology, Shenzhen, Guangdong, China. Electronic address: weizy@sustech.edu.cn.

J Biol Chem ; 299(6): 104808, 2023 06.

Article en En | MEDLINE | ID: mdl-37172719

Asunto(s)

Proteínas Adaptadoras Transductoras de Señales; Vesículas Cubiertas; Proteínas del Tejido Nervioso; Proteínas de Unión al GTP rab; Proteínas Adaptadoras Transductoras de Señales/química; Proteínas Adaptadoras Transductoras de Señales/metabolismo; Vesículas Cubiertas/química; Vesículas Cubiertas/metabolismo; Exocitosis; Liposomas; Proteínas del Tejido Nervioso/química; Proteínas del Tejido Nervioso/metabolismo; Neuronas/citología; Neuronas/metabolismo; Proteínas de Unión al GTP rab/química; Proteínas de Unión al GTP rab/metabolismo

Palabras clave

BICD; CAST; Rab-binding domain; Rab6A; active zone; biological condensate; cargo unloading; intracellular transport; neuropeptide secretion; protein-protein interaction

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Vesículas Cubiertas / Proteínas de Unión al GTP rab / Proteínas Adaptadoras Transductoras de Señales / Proteínas del Tejido Nervioso Idioma: En Revista: J Biol Chem Año: 2023 Tipo del documento: Article País de afiliación: China

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