Osteoarthritis genetic risk acting on the galactosyltransferase gene COLGALT2 has opposing functional effects in articulating joint tissues.

Kehayova, Yulia S; Wilkinson, J Mark; Rice, Sarah J; Loughlin, John

Kehayova, Yulia S; Wilkinson, J Mark; Rice, Sarah J; Loughlin, John.

Afiliación

Kehayova YS; Newcastle University, Biosciences Institute, International Centre for Life, Newcastle Upon Tyne, NE1 3BZ, UK.
Wilkinson JM; Department of Oncology and Metabolism, University of Sheffield, Sheffield, UK.
Rice SJ; Newcastle University, Biosciences Institute, International Centre for Life, Newcastle Upon Tyne, NE1 3BZ, UK. sarah.rice@ncl.ac.uk.
Loughlin J; Newcastle University, Biosciences Institute, International Centre for Life, Newcastle Upon Tyne, NE1 3BZ, UK. john.loughlin@ncl.ac.uk.

Arthritis Res Ther ; 25(1): 83, 2023 05 19.

Article en En | MEDLINE | ID: mdl-37208701

Asunto(s)

Cartílago Articular; Galactosiltransferasas; Osteoartritis; Humanos; Cartílago Articular/metabolismo; Condrocitos/metabolismo; ADN/metabolismo; Metilación de ADN/genética; Galactosiltransferasas/genética; Galactosiltransferasas/metabolismo; Osteoartritis/genética; Osteoartritis/metabolismo; Factores de Riesgo

Palabras clave

COLGALT2; DNA methylation; Epigenetics; Genetics; Synovium

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Osteoartritis / Cartílago Articular / Galactosiltransferasas Tipo de estudio: Etiology_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: Arthritis Res Ther Asunto de la revista: REUMATOLOGIA Año: 2023 Tipo del documento: Article País de afiliación: Reino Unido

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