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Stabilization of pre-existing neurotensin receptor conformational states by ß-arrestin-1 and the biased allosteric modulator ML314.
Bumbak, Fabian; Bower, James B; Zemmer, Skylar C; Inoue, Asuka; Pons, Miquel; Paniagua, Juan Carlos; Yan, Fei; Ford, James; Wu, Hongwei; Robson, Scott A; Bathgate, Ross A D; Scott, Daniel J; Gooley, Paul R; Ziarek, Joshua J.
Afiliación
  • Bumbak F; Department of Molecular and Cellular Biochemistry, Indiana University, Bloomington, IN, 47405, USA. fabian.bumbak@monash.edu.
  • Bower JB; ARC Centre for Cryo-electron Microscopy of Membrane Proteins and Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, VIC, 3052, Australia. fabian.bumbak@monash.edu.
  • Zemmer SC; Department of Molecular and Cellular Biochemistry, Indiana University, Bloomington, IN, 47405, USA.
  • Inoue A; Department of Molecular and Cellular Biochemistry, Indiana University, Bloomington, IN, 47405, USA.
  • Pons M; Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Miyagi, 980-8578, Japan.
  • Paniagua JC; Biomolecular NMR laboratory, Department of Inorganic and Organic Chemistry, Universitat de Barcelona (UB), 08028, Barcelona, Spain.
  • Yan F; Department of Materials Science and Physical Chemistry & Institute of Theoretical and Computational Chemistry (IQTCUB), Universitat de Barcelona (UB), 08028, Barcelona, Spain.
  • Ford J; Department of Biochemistry and Pharmacology, Bio21 Molecular Science and Biotechnology Institute, University of Melbourne, Parkville, VIC, 3010, Australia.
  • Wu H; Department of Chemistry, Indiana University, Bloomington, IN, 47405-7102, USA.
  • Robson SA; Department of Chemistry, Indiana University, Bloomington, IN, 47405-7102, USA.
  • Bathgate RAD; School of Chemistry & Biochemistry, Georgia Institute of Technology, Atlanta, GA, 30332, USA.
  • Scott DJ; Department of Molecular and Cellular Biochemistry, Indiana University, Bloomington, IN, 47405, USA.
  • Gooley PR; The Florey Institute of Neuroscience and Mental Health and Department of Biochemistry and Pharmacology, The University of Melbourne, Parkville, VIC, 3010, Australia.
  • Ziarek JJ; The Florey Institute of Neuroscience and Mental Health and Department of Biochemistry and Pharmacology, The University of Melbourne, Parkville, VIC, 3010, Australia.
Nat Commun ; 14(1): 3328, 2023 06 07.
Article en En | MEDLINE | ID: mdl-37286565
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Receptores de Neurotensina / Receptores Acoplados a Proteínas G Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Receptores de Neurotensina / Receptores Acoplados a Proteínas G Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos