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Fruquintinib versus placebo in patients with refractory metastatic colorectal cancer (FRESCO-2): an international, multicentre, randomised, double-blind, phase 3 study.
Dasari, Arvind; Lonardi, Sara; Garcia-Carbonero, Rocio; Elez, Elena; Yoshino, Takayuki; Sobrero, Alberto; Yao, James; García-Alfonso, Pilar; Kocsis, Judit; Cubillo Gracian, Antonio; Sartore-Bianchi, Andrea; Satoh, Taroh; Randrian, Violaine; Tomasek, Jiri; Chong, Geoff; Paulson, Andrew Scott; Masuishi, Toshiki; Jones, Jeremy; Csoszi, Tibor; Cremolini, Chiara; Ghiringhelli, Francois; Shergill, Ardaman; Hochster, Howard S; Krauss, John; Bassam, Ali; Ducreux, Michel; Elme, Anneli; Faugeras, Laurence; Kasper, Stefan; Van Cutsem, Eric; Arnold, Dirk; Nanda, Shivani; Yang, Zhao; Schelman, William R; Kania, Marek; Tabernero, Josep; Eng, Cathy.
Afiliación
  • Dasari A; Department of Gastrointestinal Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, USA. Electronic address: adasari@mdanderson.org.
  • Lonardi S; Medical Oncology Unit 1, Veneto Institute of Oncology IOV-IRCCS Padua, Padua, Italy.
  • Garcia-Carbonero R; Oncology Department, Hospital Universitario 12 de Octubre, lmas12, UCM, Madrid, Spain.
  • Elez E; Vall d'Hebron Barcelona Hospital Campus, Vall d'Hebron Institute of Oncology, Universitat Autònoma de Barcelona, Barcelona, Spain.
  • Yoshino T; Department of Gastroenterology and Gastrointestinal Oncology, National Cancer Center Hospital East, Kashiwa, Japan.
  • Sobrero A; Department of Medical Oncology, Azienda Ospedaliera San Martino, Genoa, Italy.
  • Yao J; Department of Gastrointestinal Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • García-Alfonso P; Medical Oncology Service, Hospital General Universitario Gregorio Marañón, Instituto de Investigación Sanitaria Gregorio Marañón (IiSGM), Universidad Complutense, Madrid, Spain.
  • Kocsis J; Department of Oncoradiology, Bács -Kiskun Megyei Oktatókórház, Kecskemét, Hungary.
  • Cubillo Gracian A; Medical Oncology, Hospital Universitario HM Sanchinarro Centro Integral Oncológico Clara Campal, Madrid, Spain.
  • Sartore-Bianchi A; Grande Ospedale Metropolitano Niguarda, Milan, Italy; Department of Oncology and Hemato-Oncology, Università degli Studi di Milano, Milan, Italy.
  • Satoh T; Palliative and Supportive Care Center, Osaka University Hospital, Osaka, Japan.
  • Randrian V; Department of Hepato-Gastroenterology, CHU Poitiers, Université de Poitiers, Poitiers, France.
  • Tomasek J; Department of Complex Oncology Care, Masaryk Memorial Cancer Institute, Brno, Czech Republic.
  • Chong G; Olivia Newton-John Cancer Wellness & Research Centre, Austin Hospital, Melbourne, VIC, Australia.
  • Paulson AS; Texas Oncology-Baylor Charles A Sammons Cancer Center, US Oncology Research, Dallas, TX, USA.
  • Masuishi T; Department of Clinical Oncology, Aichi Cancer Center Hospital, Aichi, Japan.
  • Jones J; Division of Hematology and Medical Oncology, Mayo Clinic Cancer Center, Jacksonville, FL, USA.
  • Csoszi T; Hetényi Géza Kórház, Onkológiai Központ, Szolnok, Hungary.
  • Cremolini C; Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, Pisa, Italy.
  • Ghiringhelli F; Department of Medical Oncology, Centre Georges François Leclerc, Dijon, France.
  • Shergill A; University of Chicago, Biological Sciences Division, Chicago, IL, USA.
  • Hochster HS; Rutgers Cancer Institute of New Jersey, New Brunswick, NJ, USA.
  • Krauss J; Department of Medicine, University of Michigan, Ann Arbor, MI, USA.
  • Bassam A; Békés Megyei Központi Kórház, Pándy Kálmán Tagkórház, Megyei Onkológiai Központ, Gyula, Hungary.
  • Ducreux M; Gustave Roussy Cancer Center, Inserm U1279 Tumors Cell Dynamics, Université Paris Saclay, Villejuif, France.
  • Elme A; Oncology and Haematology Clinic, North Estonia Medical Centre, Tallinn, Estonia.
  • Faugeras L; Department of Oncology, CHU UCL Namur, Site Godinne, Yvoir, Belgium.
  • Kasper S; Department of Medical Oncology, West German Cancer Center, University Hospital Essen, Essen, Germany.
  • Van Cutsem E; University Hospitals Gasthuisberg, Leuven and KU Leuven, Leuven, Belgium.
  • Arnold D; Asklepios Tumorzentrum Hamburg, Department of Oncology and Hematology, AK Altona, Hamburg, Germany.
  • Nanda S; HUTCHMED International Corporation, Florham Park, NJ, USA.
  • Yang Z; HUTCHMED International Corporation, Florham Park, NJ, USA.
  • Schelman WR; HUTCHMED International Corporation, Florham Park, NJ, USA.
  • Kania M; HUTCHMED International Corporation, Florham Park, NJ, USA.
  • Tabernero J; Vall d'Hebron Barcelona Hospital Campus, Vall d'Hebron Institute of Oncology (VHIO), IOB-Quiron, Barcelona, Spain.
  • Eng C; Division Hematology and Oncology, Vanderbilt-Ingram Cancer Center, Nashville, TN, USA.
Lancet ; 402(10395): 41-53, 2023 07 01.
Article en En | MEDLINE | ID: mdl-37331369
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Neoplasias del Recto / Neoplasias Colorrectales / Neoplasias del Colon Tipo de estudio: Clinical_trials Límite: Humans Idioma: En Revista: Lancet Año: 2023 Tipo del documento: Article
Texto completo
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PubMed Links
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Neoplasias del Recto / Neoplasias Colorrectales / Neoplasias del Colon Tipo de estudio: Clinical_trials Límite: Humans Idioma: En Revista: Lancet Año: 2023 Tipo del documento: Article