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DosEmi study protocol: a phase IV, multicentre, open-label, crossover study to evaluate non-inferiority of pharmacokinetic-guided reduced dosing compared with conventional dosing of emicizumab in people with haemophilia A.
Donners, Anouk; van der Zwet, Konrad; Egberts, Antoine C G; Fijnvandraat, Karin; Mathôt, Ron; Kruis, Ilmar; Cnossen, Marjon H; Schutgens, Roger; Urbanus, Rolf T; Fischer, Kathelijn.
Afiliación
  • Donners A; Department of Clinical Pharmacy, University Medical Centre, Utrecht University, Utrecht, The Netherlands.
  • van der Zwet K; Center for Benign Haematology, Thrombosis and Haemostasis, Van Creveldkliniek, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.
  • Egberts ACG; Department of Clinical Pharmacy, University Medical Centre, Utrecht University, Utrecht, The Netherlands.
  • Fijnvandraat K; Department of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Faculty of Science, Utrecht University, Utrecht, The Netherlands.
  • Mathôt R; Department of Pediatric Hematology, Emma Children's Hospital, Amsterdam University Medical Centres, University of Amsterdam, Amsterdam, The Netherlands.
  • Kruis I; Department of Hospital Pharmacy-Clinical Pharmacology, Amsterdam University Medical Centres, Amsterdam, The Netherlands.
  • Cnossen MH; Netherlands Haemophilia Society, Nijkerk, The Netherlands.
  • Schutgens R; Department of Paediatric Haematology and Oncology, Erasmus MC Sophia Children's Hospital, Erasmus University Medical Centre Rotterdam, Rotterdam, The Netherlands.
  • Urbanus RT; Principal Investigator SYMPHONY NWO-NWA Consortium, Rotterdam, The Netherlands.
  • Fischer K; Center for Benign Haematology, Thrombosis and Haemostasis, Van Creveldkliniek, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.
BMJ Open ; 13(6): e072363, 2023 06 26.
Article en En | MEDLINE | ID: mdl-37369395
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Anticuerpos Biespecíficos / Hemofilia A Tipo de estudio: Clinical_trials / Guideline Límite: Humans Idioma: En Revista: BMJ Open Año: 2023 Tipo del documento: Article País de afiliación: Países Bajos
Texto completo
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XML
PubMed Links
Buscar en Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Anticuerpos Biespecíficos / Hemofilia A Tipo de estudio: Clinical_trials / Guideline Límite: Humans Idioma: En Revista: BMJ Open Año: 2023 Tipo del documento: Article País de afiliación: Países Bajos