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Single Mutations in Cytochrome P450 Oxidoreductase Can Alter the Specificity of Human Cytochrome P450 1A2-Mediated Caffeine Metabolism.
Esteves, Francisco; Almeida, Cristina M M; Silva, Sofia; Saldanha, Inês; Urban, Philippe; Rueff, José; Pompon, Denis; Truan, Gilles; Kranendonk, Michel.
Afiliación
  • Esteves F; ToxOmics, NOVA Medical School, Faculdade de Ciências Médicas, NMS|FCM, Universidade NOVA de Lisboa, Campo Mártires da Pátria 130, 1169-056 Lisbon, Portugal.
  • Almeida CMM; iMed.UL (Institute for Medicines and Pharmaceutical Sciences, Portugal), Faculty of Pharmacy, University of Lisboa, Av. Prof. Gama Pinto, 2, 1649-003 Lisbon, Portugal.
  • Silva S; Laboratory of Bromatology and Water Quality, Faculty of Pharmacy, University of Lisbon, Av. Prof. Gama Pinto, 2, 1649-003 Lisbon, Portugal.
  • Saldanha I; Laboratory of Bromatology and Water Quality, Faculty of Pharmacy, University of Lisbon, Av. Prof. Gama Pinto, 2, 1649-003 Lisbon, Portugal.
  • Urban P; ToxOmics, NOVA Medical School, Faculdade de Ciências Médicas, NMS|FCM, Universidade NOVA de Lisboa, Campo Mártires da Pátria 130, 1169-056 Lisbon, Portugal.
  • Rueff J; TBI, Université de Toulouse, CNRS, INRAE, INSA, 135 Avenue de Rangueil, 31077 Toulouse, CEDEX 04, France.
  • Pompon D; ToxOmics, NOVA Medical School, Faculdade de Ciências Médicas, NMS|FCM, Universidade NOVA de Lisboa, Campo Mártires da Pátria 130, 1169-056 Lisbon, Portugal.
  • Truan G; TBI, Université de Toulouse, CNRS, INRAE, INSA, 135 Avenue de Rangueil, 31077 Toulouse, CEDEX 04, France.
  • Kranendonk M; TBI, Université de Toulouse, CNRS, INRAE, INSA, 135 Avenue de Rangueil, 31077 Toulouse, CEDEX 04, France.
Biomolecules ; 13(7)2023 07 06.
Article en En | MEDLINE | ID: mdl-37509119
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Cafeína / Citocromo P-450 CYP1A2 Límite: Humans Idioma: En Revista: Biomolecules Año: 2023 Tipo del documento: Article País de afiliación: Portugal
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Cafeína / Citocromo P-450 CYP1A2 Límite: Humans Idioma: En Revista: Biomolecules Año: 2023 Tipo del documento: Article País de afiliación: Portugal