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The identification of distinct protective and susceptibility mechanisms for hip osteoarthritis: findings from a genome-wide association study meta-analysis of minimum joint space width and Mendelian randomisation cluster analyses.
Faber, Benjamin G; Frysz, Monika; Boer, Cindy G; Evans, Daniel S; Ebsim, Raja; Flynn, Kaitlyn A; Lundberg, Mischa; Southam, Lorraine; Hartley, April; Saunders, Fiona R; Lindner, Claudia; Gregory, Jennifer S; Aspden, Richard M; Lane, Nancy E; Harvey, Nicholas C; Evans, David M; Zeggini, Eleftheria; Davey Smith, George; Cootes, Timothy; Van Meurs, Joyce; Kemp, John P; Tobias, Jonathan H.
Afiliación
  • Faber BG; Musculoskeletal Research Unit, University of Bristol, UK; Medical Research Council Integrative Epidemiology Unit at the University of Bristol, UK. Electronic address: ben.faber@bristol.ac.uk.
  • Frysz M; Musculoskeletal Research Unit, University of Bristol, UK; Medical Research Council Integrative Epidemiology Unit at the University of Bristol, UK.
  • Boer CG; Department of Internal Medicine, Erasmus Medical Centre, Rotterdam, the Netherlands.
  • Evans DS; California Pacific Medical Center Research Institute, San Francisco, USA.
  • Ebsim R; Division of Informatics, Imaging and Data Sciences, The University of Manchester, UK.
  • Flynn KA; Mater Research Institute, The University of Queensland, Woolloongabba, Australia; Institute for Molecular Bioscience, The University of Queensland, St Lucia, Australia.
  • Lundberg M; UQ Frazer Institute, The University of Queensland, Woolloongabba, Australia.
  • Southam L; Institute of Translational Genomics, Helmholtz Zentrum München - German Research Centre for Environmental Health, Neuherberg, Germany.
  • Hartley A; Medical Research Council Integrative Epidemiology Unit at the University of Bristol, UK.
  • Saunders FR; Centre for Arthritis and Musculoskeletal Health, University of Aberdeen, UK.
  • Lindner C; Division of Informatics, Imaging and Data Sciences, The University of Manchester, UK.
  • Gregory JS; Centre for Arthritis and Musculoskeletal Health, University of Aberdeen, UK.
  • Aspden RM; Centre for Arthritis and Musculoskeletal Health, University of Aberdeen, UK.
  • Lane NE; Center for Musculoskeletal Health, University of California Davis, Sacramento, USA.
  • Harvey NC; Medical Research Council Lifecourse Epidemiology Centre, University of Southampton, UK; NIHR Southampton Biomedical Research Centre, University of Southampton and University Hospital Southampton NHS Foundation Trust, UK.
  • Evans DM; Medical Research Council Integrative Epidemiology Unit at the University of Bristol, UK; Institute for Molecular Bioscience, The University of Queensland, St Lucia, Australia; UQ Frazer Institute, The University of Queensland, Woolloongabba, Australia.
  • Zeggini E; Institute of Translational Genomics, Helmholtz Zentrum München - German Research Centre for Environmental Health, Neuherberg, Germany; Technical University of Munich and Klinikum Rechts der Isar, TUM School of Medicine, Germany.
  • Davey Smith G; Medical Research Council Integrative Epidemiology Unit at the University of Bristol, UK.
  • Cootes T; Division of Informatics, Imaging and Data Sciences, The University of Manchester, UK.
  • Van Meurs J; Department of Internal Medicine, Erasmus Medical Centre, Rotterdam, the Netherlands.
  • Kemp JP; Medical Research Council Integrative Epidemiology Unit at the University of Bristol, UK; Mater Research Institute, The University of Queensland, Woolloongabba, Australia; Institute for Molecular Bioscience, The University of Queensland, St Lucia, Australia.
  • Tobias JH; Musculoskeletal Research Unit, University of Bristol, UK; Medical Research Council Integrative Epidemiology Unit at the University of Bristol, UK.
EBioMedicine ; 95: 104759, 2023 Sep.
Article en En | MEDLINE | ID: mdl-37619450

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Osteoartritis de la Cadera / Estudio de Asociación del Genoma Completo Tipo de estudio: Clinical_trials / Diagnostic_studies / Prognostic_studies / Risk_factors_studies / Systematic_reviews Límite: Humans Idioma: En Revista: EBioMedicine Año: 2023 Tipo del documento: Article

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Osteoartritis de la Cadera / Estudio de Asociación del Genoma Completo Tipo de estudio: Clinical_trials / Diagnostic_studies / Prognostic_studies / Risk_factors_studies / Systematic_reviews Límite: Humans Idioma: En Revista: EBioMedicine Año: 2023 Tipo del documento: Article